[ASAP] GPR120/FFAR4 Pharmacology: Focus on Agonists in Type 2 Diabetes Mellitus Drug Discovery

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c01002

1d

[ASAP] Prodrugs of a 1′-CN-4-Aza-7,9-dideazaadenosine <italic toggle="yes">C</italic>-Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial Virus with Efficacy in the African Green Monkey Model of RSV

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.1c00071

2d

[ASAP] Targeting Chikungunya Virus Replication by Benzoannulene Inhibitors

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c02183

2d

[ASAP] Discovery of 5-(3-Chlorophenylamino)benzo[<italic toggle="yes">c</italic>][2,6]naphthyridine Derivatives as Highly Selective CK2 Inhibitors with Potent Cancer Cell Stemness Inhibition

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.1c00131

3d

[ASAP] Insights into SARS-CoV-2’s Mutations for Evading Human Antibodies: Sacrifice and Survival

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.1c00311

3d

[ASAP] Tetrahydroquinoline-Capped Histone Deacetylase 6 Inhibitor SW-101 Ameliorates Pathological Phenotypes in a Charcot–Marie–Tooth Type 2A Mouse Model

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c02210

3d

[ASAP] Discovery of AG-270, a First-in-Class Oral MAT2A Inhibitor for the Treatment of Tumors with Homozygous <italic toggle="yes">MTAP</italic> Deletion

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c01895

4d

[ASAP] Sustainable Drug Discovery of Multi-Target-Directed Ligands for Alzheimer’s Disease

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.1c00048

4d

[ASAP] A New Turn in Peptide-Based Imaging Agents: Foldamers Afford Improved Theranostics Targeting Cholecystokinin-2 Receptor-Positive Cancer

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c02213

4d

[ASAP] Identification, Characterization, and Suppression of Side Products Formed during the Synthesis of [¹⁷⁷Lu]Lu-PSMA-617

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.1c00045

4d