[ASAP] Development of an Easily Bioconjugatable Water-Soluble Single-Photon Emission-Computed Tomography/Optical Imaging Bimodal Imaging Probe Based on the aza-BODIPY Fluorophore

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.1c00450

7h

[ASAP] Rational Design of Original Fused-Cycle Selective Inhibitors of Tryptophan 2,3-Dioxygenase

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.1c00323

7h

[ASAP] Design, Optimization, and Structural Characterization of an Apoptosis-Inducing Factor Peptide Targeting Human Cyclophilin A to Inhibit Apoptosis Inducing Factor-Mediated Cell Death

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.1c00777

7h

[ASAP] Xanthine Derivatives Reveal an Allosteric Binding Site in Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2)

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.1c00663

11h

[ASAP] Identification of Pyrimidine-Based Lead Compounds for Understudied Kinases Implicated in Driving Neurodegeneration

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.1c00440

1d

[ASAP] High-Throughput Crystallography Reveals Boron-Containing Inhibitors of a Penicillin-Binding Protein with Di- and Tricovalent Binding Modes

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.1c00717

2d

[ASAP] Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2<italic toggle="yes">H</italic>-benzo[<italic toggle="yes">b</italic>][1,4]oxazin-6-yl Moiety

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.1c00432

3d

[ASAP] Synthetic Peptides That Antagonize the Angiotensin-Converting Enzyme-2 (ACE-2) Interaction with SARS-CoV-2 Receptor Binding Spike Protein

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.1c00477

3d

[ASAP] Identification of Thieno[3,2-<italic toggle="yes">d</italic>]pyrimidine Derivatives as Dual Inhibitors of Focal Adhesion Kinase and FMS-like Tyrosine Kinase 3

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.1c00459

4d

[ASAP] Design and Synthesis of Novel c-di-GMP G-Quadruplex Inducers as Bacterial Biofilm Inhibitors

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.1c00465

4d