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Articles and research papers on cell division, cell structure, animal and plant cell biology and cell cycles.

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Publisher Correction: Histone variant H3.3 maintains adult haematopoietic stem cell homeostasis by enforcing chromatin adaptability

Nature Cell Biology, Published online: 20 January 2022; doi:10.1038/s41556-022-00851-wPublisher Correction: Histone variant H3.3 maintains adult haematopoietic stem cell homeostasis by enforcing chromatin adaptability

Publisher Correction: Histone variant H3.3 maintains adult haematopoietic stem cell homeostasis by enforcing chromatin adaptability

53BP1–shieldin-dependent DSB processing in BRCA1-deficient cells requires CST–Polα–primase fill-in synthesis

Nature Cell Biology, Published online: 13 January 2022; doi:10.1038/s41556-021-00812-9Mirman et al. report that the primary function of the shieldin complex in double-strand break repair in BRCA1-deficient cells is the recruitment of the CST–Polα–primase complex to conduct fill-in synthesis.

Positive feedback amplifies ferroptosis

Nature Cell Biology, Published online: 13 January 2022; doi:10.1038/s41556-021-00824-5Lipid metabolism is crucial for the execution of ferroptosis. A new study demonstrates that the function of the lipid metabolic enzyme ACSL4 is positively regulated by phosphorylation, leading to amplification of ferroptotic cell death. These results shed new light...

Enhancing T cell therapy

Nature Cell Biology, Published online: 13 January 2022; doi:10.1038/s41556-021-00831-6Enhancing T cell therapy

Nuclear access control by force

Nature Cell Biology, Published online: 13 January 2022; doi:10.1038/s41556-021-00829-0Nuclear access control by force

RNA releases CTCF from chromatin

Nature Cell Biology, Published online: 13 January 2022; doi:10.1038/s41556-021-00828-1RNA releases CTCF from chromatin

BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2

Nature Cell Biology, Published online: 13 January 2022; doi:10.1038/s41556-021-00821-8Samelson et al. report that BRD2 inhibition suppresses SARS-CoV-2 infection in epithelial cells and Syrian hamsters via reducing the transcription of host cell surface receptor ACE2.

Migrating down a hard path

Nature Cell Biology, Published online: 13 January 2022; doi:10.1038/s41556-021-00830-7Migrating down a hard path

Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis

Nature Cell Biology, Published online: 13 January 2022; doi:10.1038/s41556-021-00822-7Das et al. show that the copper transporter CTR1 functions as a redox sensor in endothelial cells. CTR1 is modified after redox stress, which induces CTR1–VEGFR2 complex formation and promotes VEGFR2 signalling and angiogenesis.

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