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Nature Communications is an online-only, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, physical and chemical sciences. Papers published by the journal represent important advances of significa

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Realization of acoustic spin transport in metasurface waveguides

Nature Communications, Published online: 18 September 2020; doi:10.1038/s41467-020-18599-ySpin angular momenta play a crucial role in topological phases of matter, in acoustic waves they have been demonstrated recently. Here, the authors present a symmetry-breaking metasurface waveguide that assists backscattering suppression of acoustic waves, because...

Ultrasensitive and visual detection of SARS-CoV-2 using all-in-one dual CRISPR-Cas12a assay

Nature Communications, Published online: 18 September 2020; doi:10.1038/s41467-020-18575-6Rapid and early detection of SARS-CoV-2 will aid intervention to stop disease spread. Here the authors present a one-pot CRISPR-based rapid detection system with visual readout.

Structural and mechanistic basis of capsule <i>O</i>-acetylation in <i>Neisseria meningitidis</i> serogroup A

Nature Communications, Published online: 18 September 2020; doi:10.1038/s41467-020-18464-yNeisseria meningitidis capsular polysaccharide (CPS) is a major virulence factor and vaccine formulations against Neisseria meningitidis serogroup A (NmA) contain O-acetylated CPS. Here, the authors provide mechanistic insights into CPS O-acetylation in NmA by...

SPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells

Nature Communications, Published online: 18 September 2020; doi:10.1038/s41467-020-18549-8Cancer stem cells can evade treatment. Here, the authors perform an in vitro screen to identify proteins that are involved in protecting glioma cancer stem cells from therapy and find that SPT6 increases BRCA1 expression and drives error-free DNA repair, thereby...

Hot electrons in a nanowire hard X-ray detector

Nature Communications, Published online: 18 September 2020; doi:10.1038/s41467-020-18384-xDesigning efficient nanowire chip-based electrical and optical devices remains a challenge. Here, the authors present an axial p-n junction GaAs nanowire X-ray detector that enables achieving a spatial resolution of 200 nm; probing the internal electrical field...

Retrieving functional pathways of biomolecules from single-particle snapshots

Nature Communications, Published online: 18 September 2020; doi:10.1038/s41467-020-18403-xThere is a great interest in retrieving functional pathways from cryo-EM single-particle data. Here, the authors present an approach that combines cryo-EM with advanced data-analytical methods and molecular dynamics simulations to reveal the functional pathways...

Three-dimensional strain dynamics govern the hysteresis in heterogeneous catalysis

Nature Communications, Published online: 18 September 2020; doi:10.1038/s41467-020-18622-2Direct visualisation of site-specific strain variations of catalysts is needed to better understand catalytic properties. Here, the authors determine with attojoule precision that the well-known catalytic hysteresis phenomenon occurs at single particle level and...

DsbA-L mediated renal tubulointerstitial fibrosis in UUO mice

Nature Communications, Published online: 18 September 2020; doi:10.1038/s41467-020-18304-zDsbA-L upregulation prevents lipid-induced renal injury in diabetic nephropathy. Here, the authors show that DsbA-L knockout attenuates tubulointerstitial fibrosis in mice, and show that this occurs via activation of Smad3 and p53, which result in modulation of...

SPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells

Structural and mechanistic basis of capsule <i>O</i>-acetylation in <i>Neisseria meningitidis</i> serogroup A

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