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Nature Genetics publishes the very highest quality research in genetics. It encompasses genetic and functional genomic studies on human traits and on other model organisms, including mouse, fly, nematode and yeast. Current emphasis is on the genetic

Latest articles

A functional genomics predictive network model identifies regulators of inflammatory bowel disease

Nature Genetics. doi:10.1038/ng.3947 Authors: Lauren A Peters, Jacqueline Perrigoue, Arthur Mortha, Alina Iuga, Won-min Song, Eric M Neiman, Sean R Llewellyn, Antonio Di Narzo, Brian A Kidd, Shannon E Telesco, Yongzhong Zhao, Aleksandar Stojmirovic, Jocelyn Sendecki, Khader Shameer, Riccardo Miotto, Bojan Losic, Hardik Shah, Eunjee...

Interpreting short tandem repeat variations in humans using mutational constraint

Nature Genetics. doi:10.1038/ng.3952 Authors: Melissa Gymrek, Thomas Willems, David Reich & Yaniv Erlich

Genome-wide association study identifies 112 new loci for body mass index in the Japanese population

Nature Genetics. doi:10.1038/ng.3951 Authors: Masato Akiyama, Yukinori Okada, Masahiro Kanai, Atsushi Takahashi, Yukihide Momozawa, Masashi Ikeda, Nakao Iwata, Shiro Ikegawa, Makoto Hirata, Koichi Matsuda, Motoki Iwasaki, Taiki Yamaji, Norie Sawada, Tsuyoshi Hachiya, Kozo Tanno, Atsushi Shimizu, Atsushi Hozawa, Naoko Minegishi, Shoichiro...

A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci

Nature Genetics. doi:10.1038/ng.3955 Authors: Diana Chang, Mike A Nalls, Ingileif B Hallgrímsdóttir, Julie Hunkapiller, Marcel van der Brug, Fang Cai, Geoffrey A Kerchner, Gai Ayalon, Baris Bingol, Morgan Sheng, David Hinds, Timothy W Behrens, Andrew B Singleton, Tushar R Bhangale & Robert R Graham Common variant genome-wide association...

Linkage disequilibrium–dependent architecture of human complex traits shows action of negative selection

Nature Genetics. doi:10.1038/ng.3954 Authors: Steven Gazal, Hilary K Finucane, Nicholas A Furlotte, Po-Ru Loh, Pier Francesco Palamara, Xuanyao Liu, Armin Schoech, Brendan Bulik-Sullivan, Benjamin M Neale, Alexander Gusev & Alkes L Price

Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis

Nature Genetics. doi:10.1038/ng.3949 Authors: John P Kemp, John A Morris, Carolina Medina-Gomez, Vincenzo Forgetta, Nicole M Warrington, Scott E Youlten, Jie Zheng, Celia L Gregson, Elin Grundberg, Katerina Trajanoska, John G Logan, Andrea S Pollard, Penny C Sparkes, Elena J Ghirardello, Rebecca Allen, Victoria D Leitch, Natalie C...

Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease

Nature Genetics. doi:10.1038/ng.3943 Authors: Wei Zhao, Asif Rasheed, Emmi Tikkanen, Jung-Jin Lee, Adam S Butterworth, Joanna M M Howson, Themistocles L Assimes, Rajiv Chowdhury, Marju Orho-Melander, Scott Damrauer, Aeron Small, Senay Asma, Minako Imamura, Toshimasa Yamauch, John C Chambers, Peng Chen, Bishwa R Sapkota, Nabi Shah,...

Reconstruction of enhancer–target networks in 935 samples of human primary cells, tissues and cell lines

Nature Genetics. doi:10.1038/ng.3950 Authors: Qin Cao, Christine Anyansi, Xihao Hu, Liangliang Xu, Lei Xiong, Wenshu Tang, Myth T S Mok, Chao Cheng, Xiaodan Fan, Mark Gerstein, Alfred S L Cheng & Kevin Y Yip

LINE-1 activation after fertilization regulates global chromatin accessibility in the early mouse embryo

Nature Genetics. doi:10.1038/ng.3945 Authors: Joanna W Jachowicz, Xinyang Bing, Julien Pontabry, Ana Bošković, Oliver J Rando & Maria-Elena Torres-Padilla

Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog)

Nature Genetics. doi:10.1038/ng.3939 Authors: Anja J Will, Giulia Cova, Marco Osterwalder, Wing-Lee Chan, Lars Wittler, Norbert Brieske, Verena Heinrich, Jean-Pierre de Villartay, Martin Vingron, Eva Klopocki, Axel Visel, Darío G Lupiáñez & Stefan Mundlos Copy number variations (CNVs) often include noncoding sequences and putative...

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