Nature Genetics publishes the very highest quality research in genetics. It encompasses genetic and functional genomic studies on human traits and on other model organisms, including mouse, fly, nematode and yeast. Current emphasis is on the genetic
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Genomic variation in weedy and cultivated broomcorn millet accessions uncovers the genetic architecture of agronomic traits

Nature Genetics, Published online: 24 April 2024; doi:10.1038/s41588-024-01718-6A comprehensive variation map constructed by deep sequencing 1,904 accessions of weedy and cultivated broomcorn millet sheds light on the genetic architecture of agronomic traits during domestication.

Wed Apr 24, 2024 14:06
Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification

Nature Genetics, Published online: 24 April 2024; doi:10.1038/s41588-024-01726-6BEAN is a Bayesian approach for analyzing base editing screens with improved effect size quantification and variant classification. Applied to low-density lipoprotein (LDL)-associated common variants and saturation base editing of LDLR, BEAN identifies new LDL uptake genes...

Wed Apr 24, 2024 14:06
New genes helped acorn barnacles adapt to a sessile lifestyle

Nature Genetics, Published online: 23 April 2024; doi:10.1038/s41588-024-01733-7A new acorn barnacles genome assembly, together with transcriptomic and proteomic datasets and functional experiments, identify bcs-6 and bsf, as new genes involved in the settlement process by facilitating energy metabolism and stabilizing the alternating layers of chitin...

Tue Apr 23, 2024 17:02
Finding the lost sister: mirror-image mutation phasing in mammalian mitotic sister cells

Nature Genetics, Published online: 22 April 2024; doi:10.1038/s41588-024-01713-xThis study establishes in vitro and in vivo systems to study mutagenesis and cancer genome evolution. Using microfluidics and mouse models, the method enables the dissection of co-occurring mutational processes and reveals that acute damage results in mirror-image mutation...

Mon Apr 22, 2024 23:00
Differential selection of yield and quality traits has shaped genomic signatures of cowpea domestication and improvement

Nature Genetics, Published online: 22 April 2024; doi:10.1038/s41588-024-01722-wHigh-quality genome assemblies of grain and vegetable cowpeas and re-sequencing of 344 accessions characterize genomic variations between cowpea subspecies and their domestication and improvement under selection.

Mon Apr 22, 2024 16:58
Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

Nature Genetics, Published online: 19 April 2024; doi:10.1038/s41588-024-01752-4Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

Fri Apr 19, 2024 19:48

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