Looking beyond COVID-19 vaccine phase 3 trials

Nature Medicine, Published online: 19 January 2021; doi:10.1038/s41591-021-01230-yA comprehensive strategy for the next steps to ensure vaccination of the global population against SARS-CoV-2 is now required, and key steps and challenges are detailed in this Perspective.

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Looking beyond COVID-19 vaccine phase 3 trials

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Antibiotic resistance: a call to action to prevent the next epidemic of inequality

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The limits of acceptable political influence over the FDA

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Impaired meningeal lymphatic drainage in patients with idiopathic Parkinson’s disease

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State-dependent responses to intracranial brain stimulation in a patient with depression

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High-frequency neuromodulation improves obsessive–compulsive behavior

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The androgen receptor is a tumor suppressor in estrogen receptor–positive breast cancer

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Durvalumab compared to maintenance chemotherapy in metastatic breast cancer: the randomized phase II SAFIR02-BREAST IMMUNO trial

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Durvalumab compared to maintenance chemotherapy in metastatic breast cancer: the randomized phase II SAFIR02-BREAST IMMUNO trial

Nature Medicine, Published online: 18 January 2021; doi:10.1038/s41591-020-01189-2Exploratory analyses from the phase 2 randomized SAFIR02-IMMUNO trial identify biomarkers associated with improved outcomes to durvalumab as compared to maintenance chemotherapy in patients with triple-negative breast cancer.

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