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Nature Medicine is the premier journal for biomedical research. Respected internationally for the quality of its papers on areas ranging from infectious disease to cancer and neurodegeneration, Nature Medicine aims to bridge the gap between basic res

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Effectiveness of CoronaVac in children 3 to 5 years during the SARS-CoV-2 Omicron outbreak in Chile

Nature Medicine, Published online: 23 May 2022; doi:10.1038/s41591-022-01874-4CoronaVac protects young children from severe COVID-19 during a SARS-CoV-2 Omicron surge, supporting the effectiveness and importance of vaccinating this pediatric population.

A multisystem, cardio-renal investigation of post-COVID-19 illness

Nature Medicine, Published online: 23 May 2022; doi:10.1038/s41591-022-01837-9Deep clinical phenotyping at 28–60 days post-discharge of patients who had been hospitalized with COVID-19 and subsequent long-term follow-up with electronic health records reveal evidence of persistent cardio-renal involvement.

Multisystem involvement is common in post-COVID-19 syndrome

Nature Medicine, Published online: 23 May 2022; doi:10.1038/s41591-022-01838-8A prospective clinical study evaluating patients 28–60 days after hospitalization for COVID-19 reveals increased cardio-renal inflammation, reduced lung function and poorer self-reported clinical outcomes in patients relative to that in control participants.

Effectiveness of CoronaVac in children 3 to 5 years during the SARS-CoV-2 Omicron outbreak in Chile

Multisystem involvement is common in post-COVID-19 syndrome

A multisystem, cardio-renal investigation of post-COVID-19 illness

Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial

Nature Medicine, Published online: 19 May 2022; doi:10.1038/s41591-022-01789-0Biomarker analysis of the phase 4 R4RA trial identifies pretreatment synovial biopsy features selectively associated with response to rituximab or tocilizumab, and leads to the development of models that might predict treatment benefit in patients with rheumatoid arthritis

Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial

<b>Ethically incorporating patient perspectives into research</b>

Nature Medicine, Published online: 19 May 2022; doi:10.1038/d41591-022-00062-8To maximize the benefits of patient-reported outcomes data while protecting patient welfare, a panel of experts set out ethical guidelines for the incorporation of these into clinical research.

<b>Finding a vaccine for Epstein-Barr virus</b>

Nature Medicine, Published online: 19 May 2022; doi:10.1038/d41591-022-00061-9Nanoparticle vaccines show promise in preclinical models; clinical evaluation is warranted to assess whether they could help reduce the burden of disease associated with EBV in humans.

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