COVID-19 may become nanomedicine’s finest hour yet

Nature Nanotechnology, Published online: 14 April 2021; doi:10.1038/s41565-021-00901-8The nanotechnology-enabled mRNA-based vaccine platform recently approved against COVID-19 bears hope for improved vaccine development and trialling capacities in low- and middle-income countries as part of a broader global public health agenda.

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Nanotechnology for infectious diseases

Nature Nanotechnology, Published online: 14 April 2021; doi:10.1038/s41565-021-00909-0To achieve the biggest impact, nanotechnology-based strategies developed to manage infectious diseases in resourced-limited settings need to take into account the local context.

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Local development of nanotechnology-based diagnostics

Nature Nanotechnology, Published online: 12 April 2021; doi:10.1038/s41565-021-00907-2Sharing protocols with the end-users may allow their flexible implementation to produce nanotechnology solutions for global health challenges that better cater for local needs.

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Local development of nanotechnology-based diagnostics

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Conformable hierarchically engineered polymeric micromeshes enabling combinatorial therapies in brain tumours

Nature Nanotechnology, Published online: 01 April 2021; doi:10.1038/s41565-021-00879-3Surgical resection is the primary treatment strategy for glioblastoma multiforme, but the infiltrating nature of the tumour, coupled with its heterogeneity and the presence of the blood–brain barrier that hampers drug delivery, contributes to recurrence and poor prognosis....

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Conformable hierarchically engineered polymeric micromeshes enabling combinatorial therapies in brain tumours

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Bioelectronic control of a microbial community using surface-assembled electrogenetic cells to route signals

Nature Nanotechnology, Published online: 29 March 2021; doi:10.1038/s41565-021-00878-4Living electrodes enable signalling into a microbial community, coordinating behaviour.

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A highly homogeneous polymer composed of tetrahedron-like monomers for high-isotropy expansion microscopy

Nature Nanotechnology, Published online: 29 March 2021; doi:10.1038/s41565-021-00875-7Expansion microscopy, or ExM, physically expands biological specimens upon embedding them in swellable polymeric hydrogels, allowing nanoscale imaging using conventional microscopes. This work presents a diamond lattice polymeric hydrogel synthesized via click chemistry,...

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Nanotechnology, equity and global health

Nature Nanotechnology, Published online: 29 March 2021; doi:10.1038/s41565-021-00899-zWhen developing nanotechnology solutions for global health it is important to be mindful of the ethical, environmental, socio-economical, cultural and legal aspects associated with their deployment.

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Ultra-high-frequency radio-frequency acoustic molecular imaging with saline nanodroplets in living subjects

Nature Nanotechnology, Published online: 29 March 2021; doi:10.1038/s41565-021-00869-5Ultra-high-frequency radio-frequency acoustic molecular imaging is a safe molecular imaging diagnostic option because it does not require radioactive probes or high magnetic fields, but lack of biocompatible targeted contrast agents has so far limited its in vivo application....

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