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Home advantage for tissue-resident macrophages

Nature Reviews Cancer, Published online: 22 July 2021; doi:10.1038/s41568-021-00393-7Casanova-Acebes et al. show that tissue-resident macrophages provide a unique niche for tumour cells in the lung to promote invasiveness and regulatory T cell-mediated immune suppression.

Home advantage for tissue-resident macrophages

Metabolic mechanisms of medulloblastoma metastasis

Nature Reviews Cancer, Published online: 19 July 2021; doi:10.1038/s41568-021-00391-9Martirosian et al. show that a metabolic mechanism used by neurons and astrocytes during periods of nutrient deprivation and stress may have a role in leptomeningeal dissemination of medulloblastoma.

Microbiota links to immunotherapy toxicity

Nature Reviews Cancer, Published online: 19 July 2021; doi:10.1038/s41568-021-00390-wAndrews et al. provide evidence that immune-related adverse events following cancer immunotherapy may be linked to the patient’s gut microbiota.

Metabolic mechanisms of medulloblastoma metastasis

Microbiota links to immunotherapy toxicity

Cancer metabolism: looking forward

Nature Reviews Cancer, Published online: 16 July 2021; doi:10.1038/s41568-021-00378-6This Perspective discusses the main themes in cancer metabolism research that are currently under investigation in the context of in vivo tumour metabolism, specifically emphasizing emerging aspects and questions that remain unanswered.

Cancer metabolism: looking forward

Metabolic networks in mutant KRAS-driven tumours: tissue specificities and the microenvironment

Nature Reviews Cancer, Published online: 09 July 2021; doi:10.1038/s41568-021-00375-9This Review examines the tissue-specific metabolism and associated therapeutic vulnerabilities of mutant KRAS-driven tumours, providing a comparative discussion of intrinsic metabolism, co-occurring mutations and metabolic interactions in the microenvironment in colorectal,...

Metabolic networks in mutant KRAS-driven tumours: tissue specificities and the microenvironment

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