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RIPK3 inhibitor prevents lung damage in severe influenza infection

Nature Reviews Drug Discovery, Published online: 24 April 2024; doi:10.1038/d41573-024-00072-wRIPK3 inhibitor prevents lung damage in severe influenza infection

Wed Apr 24, 2024 14:24
mRNA therapy shows promise for metabolic disorder

Nature Reviews Drug Discovery, Published online: 23 April 2024; doi:10.1038/d41573-024-00071-xmRNA therapy shows promise for metabolic disorder

Tue Apr 23, 2024 14:32
RNA-editing drugs advance into clinical trials

Nature Reviews Drug Discovery, Published online: 18 April 2024; doi:10.1038/d41573-024-00070-yADAR-based editors that can change the mRNA code offer new opportunities in both rare genetic diseases and common complex ones.

Thu Apr 18, 2024 16:35
Three-step cures for autoimmune diseases?

Nature Reviews Drug Discovery, Published online: 17 April 2024; doi:10.1038/d41573-024-00069-5Robert Plenge, head of Research at Bristol Myers Squibb, discusses his vision of sequential immunotherapy for autoimmune diseases — including multiple sclerosis.

Wed Apr 17, 2024 19:35
The antibody–drug conjugate landscape

Nature Reviews Drug Discovery, Published online: 16 April 2024; doi:10.1038/d41573-024-00064-wThe antibody–drug conjugate landscape

Tue Apr 16, 2024 13:37
Targeting immunogenic cell stress and death for cancer therapy

Nature Reviews Drug Discovery, Published online: 15 April 2024; doi:10.1038/s41573-024-00920-9Immunogenic cell death (ICD) is crucial for the elicitation of anticancer immune responses by therapy, but the successful development of ICD-inducing treatments is hindered by various obstacles. This Review provides an overview of the core mechanisms of ICD,...

Mon Apr 15, 2024 19:38

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