The role of ordered cooperative assembly in biomolecular condensates

Nature Reviews Molecular Cell Biology, Published online: 04 August 2021; doi:10.1038/s41580-021-00408-zIn this Comment, the authors draw attention to the role of partial order in biomolecular condensates and propose that cooperative, ordered interactions between condensate components could underlie the formation and function of these diverse macromolecular...

20h

The role of ordered cooperative assembly in biomolecular condensates

21h

Keeping oocytes young

Nature Reviews Molecular Cell Biology, Published online: 03 August 2021; doi:10.1038/s41580-021-00410-5Suppressing ovulation protects against chromosomal abnormalities in ageing mouse oocytes, which can be partly explained by increasing REC8–cohesin retention on chromosomes.

1d

Keeping oocytes young

1d

Nuclear compartmentalization as a mechanism of quantitative control of gene expression

2d

Nuclear compartmentalization as a mechanism of quantitative control of gene expression

Nature Reviews Molecular Cell Biology, Published online: 02 August 2021; doi:10.1038/s41580-021-00387-1An emerging model of gene regulation posits that DNA, RNA and proteins form condensate nuclear compartments that facilitate cooperative interactions. This Review discusses how compartmentalization can lead to non-stoichiometric molecular interactions...

2d

Voices of the new generation: establishing yourself as a PI in a competitive field

Nature Reviews Molecular Cell Biology, Published online: 30 July 2021; doi:10.1038/s41580-021-00409-yJonathon Ditlev shares his thoughts on building a research programme in a competitive field.

5d

Voices of the new generation: establishing yourself as a PI in a competitive field

5d

Dicing viral RNA in stem cells

6d

Dicing viral RNA in stem cells

Nature Reviews Molecular Cell Biology, Published online: 29 July 2021; doi:10.1038/s41580-021-00406-1RNA interference mediated by a Dicer isoform protects mammalian stem cells against RNA viruses.

6d