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Phosphoinositides as membrane organizers

Nature Reviews Molecular Cell Biology, Published online: 19 May 2022; doi:10.1038/s41580-022-00490-xPhosphoinositides are signalling, membrane lipids derived from phosphatidylinositol, whose intracellular distribution and interconversion via phosphoinositide kinases and phosphatases is tightly coupled to membrane dynamics. Accordingly, phosphoinositides...

Phosphoinositides as membrane organizers

Curvature-mediated endocytosis

Nature Reviews Molecular Cell Biology, Published online: 16 May 2022; doi:10.1038/s41580-022-00497-4Cail et al. introduce a platform to study the role of plasma membrane curvature during clathrin-mediated endocytosis.

Transcriptional control of energy metabolism by nuclear receptors

Nature Reviews Molecular Cell Biology, Published online: 16 May 2022; doi:10.1038/s41580-022-00486-7Nuclear receptors are transcription factors that transduce hormonal, nutrient, metabolite and redox signals into regulation of metabolic genes, in particular the transcriptional control of energy metabolism. Accordingly, nuclear receptors have central...

Curvature-mediated endocytosis

Transcriptional control of energy metabolism by nuclear receptors

Establishment of H3K9-methylated heterochromatin and its functions in tissue differentiation and maintenance

Nature Reviews Molecular Cell Biology, Published online: 13 May 2022; doi:10.1038/s41580-022-00483-wHistone H3 Lys9 (H3K9)-methylated heterochromatin ensures transcriptional silencing of repetitive elements and genes, and its deregulation leads to impaired cell and tissue identity, premature aging and cancer. Recent studies in mammals clarified the...

Establishment of H3K9-methylated heterochromatin and its functions in tissue differentiation and maintenance

Author Correction: The roles of Polycomb repressive complexes in mammalian development and cancer

Nature Reviews Molecular Cell Biology, Published online: 09 May 2022; doi:10.1038/s41580-022-00495-6Author Correction: The roles of Polycomb repressive complexes in mammalian development and cancer

Author Correction: The roles of Polycomb repressive complexes in mammalian development and cancer

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