Nature Reviews Microbiology, Published online: 24 April 2024; doi:10.1038/s41579-024-01052-yIn this study, Carrasco Flores et al. report that the bacterium Mycetocola lacteus protects the microalga Chlamydomonas reinhardtii from the antagonistic activity of Pseudomonas protegens.

Nature Reviews Microbiology, Published online: 24 April 2024; doi:10.1038/s41579-024-01053-xA recent study reports the existence of a nitrogen-fixing organelle called the ‘nitroplast’.

Nature Reviews Microbiology, Published online: 24 April 2024; doi:10.1038/s41579-024-01049-7In this Journal Club, Ricardo Soto-Rifo discusses a study on intron-containing HIV-1 RNA, revealing its role as a pathogen-associated molecular pattern in myeloid cells, which has implications for immune activation, inflammation and clinical outcomes.

Nature Reviews Microbiology, Published online: 22 April 2024; doi:10.1038/s41579-024-01050-0This study shows that a single-stranded RNA phage binds to the Pseudomonas aeruginosa type IV pilus, leading to phage entry into the cell and the detachment of the pilus, which impairs bacterial motility.

Nature Reviews Microbiology, Published online: 18 April 2024; doi:10.1038/s41579-024-01047-9In this study, Granton et al. show that biofilm-associated exopolysaccharides produced by Pseudomonas aeruginosa control sickness during lung infection.

Nature Reviews Microbiology, Published online: 15 April 2024; doi:10.1038/s41579-024-01036-yIn this Review, Chan et al. explore major drug discovery approaches, preclinical antiviral evaluation models, virus-targeting and host-targeting therapeutic strategies, and key treatments currently used in clinical settings for COVID-19.