by Laura Dirkx, Sara Van Acker, Yasmine Nicolaes, João Luís Reis Cunha, Rokaya Ahmad, Rik Hendrickx, Ben Caljon, Hideo Imamura, Didier G. Ebo, Daniel C. Jeffares, Yann G.-J. Sterckx, Louis Maes, Sarah Hendrickx, Guy Caljon Addressing the challenges of quiescence and post-treatment relapse is of utmost importance in the microbiology field. This...

by Chris Lauber, Xiaoyu Zhang, Josef Vaas, Franziska Klingler, Pascal Mutz, Arseny Dubin, Thomas Pietschmann, Olivia Roth, Benjamin W. Neuman, Alexander E. Gorbalenya, Ralf Bartenschlager, Stefan Seitz Virus discovery by genomics and metagenomics empowered studies of viromes, facilitated characterization of pathogen epidemiology, and redefined...

by Hagen Sülzen, Alexander N. Volkov, Rob Geens, Farnaz Zahedifard, Benoit Stijlemans, Martin Zoltner, Stefan Magez, Yann G.-J. Sterckx, Sebastian Zoll In the bloodstream of mammalian hosts, African trypanosomes face the challenge of protecting their invariant surface receptors from immune detection. This crucial role is fulfilled by a dense, glycosylated...

by Qibing Gu, Xiayu Zhu, Yong Yu, Tao Jiang, Zihao Pan, Jiale Ma, Huochun Yao Integrative and conjugative elements (ICEs) play a vital role in bacterial evolution by carrying essential genes that confer adaptive functions to the host. Despite their importance, the mechanism underlying the stable inheritance of ICEs, which is necessary for the acquisition...

by Zhiwen Wang, Shan Zhong, Sicong Zhang, Borui Zhang, Yang Zheng, Ye Sun, Qinghua Zhang, Xili Liu Proper transcription orchestrated by RNA polymerase II (RNPII) is crucial for cellular development, which is rely on the phosphorylation state of RNPII’s carboxyl-terminal domain (CTD). Sporangia, developed from mycelia, are essential for the destructive...

by Christina D. Orrú, Bradley R. Groveman, Andrew G. Hughson, Tomás Barrio, Kachi Isiofia, Brent Race, Natalia C. Ferreira, Pierluigi Gambetti, David A. Schneider, Kentaro Masujin, Kohtaro Miyazawa, Bernardino Ghetti, Gianluigi Zanusso, Byron Caughey Prions or prion-like aggregates such as those composed of PrP, α-synuclein, and tau are key features...