The Driving Force for Co-translational Protein Folding is Weaker In the Ribosome Vestibule due to Greater Water Ordering

Chem. Sci., 2021, Accepted ManuscriptDOI: 10.1039/D1SC01008E, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Quyen V Vu, Yang Jiang, Mai Suan Li, Edward O'BrienInteractions between the ribosome and nascent chain can destabilize folded domains in the ribosome exit tunnel’s vestibule, the...

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Turning Waste into Wealth: Facile and Green Synthesis of Graphene Nanodots from Pollutants and Applications to Bioimaging

Chem. Sci., 2021, Accepted ManuscriptDOI: 10.1039/D1SC02837E, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Weifeng Chen, Jialu Shen, Zuo Wang, Yanyi Xu, Xiang Liu, Haiyu Zhao, Didier AstrucIn an effort to turn waste into wealth, Reactive Red 2 (RR2), a common and refractory...

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Discovery and characterisation of an amidine-containing ribosomally-synthesised peptide that is widely distributed in nature

Chem. Sci., 2021, Accepted ManuscriptDOI: 10.1039/D1SC01456K, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Alicia H Russell, Natalia Miguel Vior, Edward Steven Hems, Rodney Lacret, Andrew William TrumanRibosomally synthesised and post-translationally modified peptides (RiPPs) are a structurally...

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Me3SiSiMe2(OnBu): A Disilane Reagent for the Synthesis of Diverse Silacycles via Brook- and Retro-Brook-Type Rearrangement

Chem. Sci., 2021, Accepted ManuscriptDOI: 10.1039/D1SC03487A, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yankun Xu, Weiwei Xu, Xinyang Chen, Xiai Luo, Haiyan Lu, Minghao Zhang, Xiumei Yang, Guobo Deng, Yun Liang, Yuan YangHerein, the readily available disilane Me3SiSiMe2(OnBu)...

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Coumarin luciferins and mutant luciferases for robust multi-component bioluminescence imaging

Chem. Sci., 2021, Advance ArticleDOI: 10.1039/D1SC03114G, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Zi Yao, Donald R. Caldwell, Anna C. Love, Bethany Kolbaba-Kartchner, Jeremy H. Mills, Martin J. Schnermann, Jennifer A. PrescherNear-infrared probes were developed from...

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On the limit of proton-coupled electronic doping in a Ti(IV)-containing MOF

Chem. Sci., 2021, Accepted ManuscriptDOI: 10.1039/D1SC03019A, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jenna L Mancuso, Kevin Fabrizio, Carl K. Brozek, Christopher H. HendonTiIV-containing metal-organic frameworks are known to accumulate electrons in their conduction...

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‘Reverse biomimetic’ synthesis of L-arogenate and its stabilized analogues from L-tyrosine

Chem. Sci., 2021, Advance ArticleDOI: 10.1039/D1SC03554A, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Louise Eagling, Daniel J. Leonard, Maria Schwarz, Iñaki Urruzuno, Grace Boden, J. Steven Wailes, John W. Ward, Jonathan ClaydenL-Tyrosine provides a precursor for a practical synthesis...

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Copper-catalyzed [3+1] cyclization of cyclopropenes/diazo compounds and bromodifluoroacetamides: facile synthesis of α,α-difluoro-β-lactam derivatives

Chem. Sci., 2021, Accepted ManuscriptDOI: 10.1039/D1SC02930D, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Mengru Zhang, Hexin Li, Jinbo Zhao, Yan Li, Qian ZhangWe have developed a novel copper-catalyzed cyclization of cyclopropenes/diazo compounds and bromodifluoroacetamides,...

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“Click-Switch” – one-step conversion of organic azides into photochromic diarylethenes for the generation of light-controlled systems

Chem. Sci., 2021, Accepted ManuscriptDOI: 10.1039/D1SC02526K, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Steffy Becht, Reena Sen, Simon M. Bullmann, Andreas Dreuw, Andres JaeschkeDiarylethenes (DAEs) are an established class of photochromic molecules, but their effective...

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Accelerating the insertion reactions of (NHC)Cu–H via remote ligand functionalization

Chem. Sci., 2021, Advance ArticleDOI: 10.1039/D1SC01911B, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Amy L. Speelman, Ba L. Tran, Jeremy D. Erickson, Monica Vasiliu, David A. Dixon, R. Morris BullockRemote modification of an N-heterocyclic carbene ligand with bulky or electron-rich groups...

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