Pathogen host shifts - where a pathogen jumps from one host species to another - are important sources of emerging infectious diseases. Although viral pathogens are a major source of emerging infectious diseases, there is a growing focus on the emergence of novel bacterial infections through host shifts. However, compared to viruses we know relatively...

Combinatorial control by multiple transcription factors (TFs) allows for increased specificity and information integration. Despite its prevalence in eukaryotes and crucial roles in gene regulation, the reason why eukaryotic TFs often depend on one another, and whether and how such codependency evolves, are not well understood. We exploit natural variation...

The tree of blobs of a species network shows only the tree-like aspects of relationships of taxa on a network, omitting information on network substructures where hybridization or other types of lateral transfer of genetic information occur. By isolating such regions of a network, inference of the tree of blobs can serve as a starting point for a more...

A critical function of central neural circuits is to integrate sensory and internal information to cause a behavioural output. Evolution modifies such circuits to generate adaptive change in sensory detection and behaviour, but it remains unclear how selection does so in the context of existing functional and developmental constraints. Here, we explore...

Many species are undergoing rapid demographic declines, necessitating an examination of the resulting genetic impacts. The prevailing small population paradigm posits an elevated genetic load and extinction risk. However, instances of fast recovery from severe population bottlenecks suggest alternative outcomes. To investigate this issue, we performed...

Despite showing the greatest primate diversity on the planet, genomic studies on Amazonian primates show very little representation in the literature. With 48 geolocalized high coverage whole genomes from wild uakari monkeys, we present the first population-level study on platyrrhines using whole genome data. In a very restricted range of the Amazon...