Asymptomatic and Symptomatic SARS-CoV-2 Infections After BNT162b2 Vaccination in a Routinely Screened Workforce

This study aims to describe an association between the Pfizer-BioNTech (BNT162b2) vaccine and decreased risk of symptomatic and asymptomatic infections with SARS-CoV-2 in hospital employees.

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Progress With the All of Us Research Program: Opening Access for Researchers

This Viewpoint summarizes enrollment to date in the All of Us Research Program, a cohort study launched in 2018 designed to enroll ≥1 million participants, including those from historically underrepresented backgrounds, to diversify the human genome database and the infrastructure it is building to broadly share its data assets to improve and accelerate...

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Vaccination in Residential Facilities

The Centers for Medicare & Medicaid Services (CMS) recently issued a rule requiring that long-term care facilities and intermediate care facilities for people with intellectual disabilities educate residents, clients, and staff about COVID-19 vaccines and offer them the shots.

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Transcatheter Treatments of Valvular Heart Disease 2020

This narrative review provides an overview of the various types of transcatheter valve therapies for individuals with either mitral or aortic valve disease that are currently available in the US and in the European Union using data from clinical trials and recommendations from 1 clinical guideline.

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NIH Addresses COVID-19 Disparities

The National Institutes of Health (NIH) recently funded $29 million in new grants to address COVID-19 disparities among racial and ethnic minorities.

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Community-Based Organizations Step Up to Confront HIV in Southern States

This Medical News article discussed the deeply rooted HIV epidemic in the US South and community-based efforts to provide prevention services and medical care.

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Audio Highlights

Listen to the JAMA Editor’s Audio Summary for an overview and discussion of the important articles appearing in this week’s issue of JAMA.

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Cerebral Venous Sinus Thrombosis With Thrombocytopenia After Ad26.COV2.S Vaccination

This study describes the reported US cases of cerebral venous sinus thrombosis (CVST) with thrombocytopenia following vaccination with Ad26.COV2.S, the COVID-19 vaccine produced by Janssen/Johnson & Johnson.

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Assessment of Depressive Symptoms in Medically Ill Patients

This JAMA Insights Clinical Update proposes an algorithm to determine the cause of depression in people with chronic and severe medical illness and summarizes screening, diagnosis, and management recommendations.

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Botulism Guidelines Aim to Help Prepare Clinicians for Outbreaks

CDC officials have issued the first comprehensive, evidence-based guidelines to help physicians, hospitals, and public health agencies respond in the event of a large-scale botulism outbreak.

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