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Patient Information: Carpal Tunnel Syndrome

This JAMA Patient Page describes carpal tunnel syndrome and its symptoms, risk factors, diagnosis, and treatment options.

Contraception in Women With Cardiovascular Disease

This JAMA Insights in Women’s Health series summarizes the prevalence of cardiovascular disease among women of childbearing age, the most effective forms of contraception based on the patient’s medical condition and preference, and the risks and adverse effects associated with contraindicated forms of contraception.

New “Universal” Flu Vaccine Candidate Enters Clinical Trial

A phase 1 clinical trial for a “universal” influenza A vaccine candidate, BPL-1357, is now underway at the National Institutes of Health (NIH) Clinical Center, the agency announced. In an animal study not yet peer reviewed, mice and ferrets that received the vaccine survived lethal doses of 6 different flu strains, including subtypes not included in...

Reading Camus in Our Time of Plague

In this narrative medicine essay, an infectious diseases physician ponders how working through the COVID pandemic has changed her even though the words to explain it elude her and finds solace in the experience described in the Camus novel The Plague.

Predicting Cancer Immunotherapy Response With Whole Exome Sequencing

An investigational tool using whole-exome sequencing (WES) more accurately identified genes and pathways that predict whether patients with cancer will respond to immune checkpoint blockade (ICB) than current tumor mutation burden (TMB) tests alone, researchers reported in Nature Communications.

Achieving Diagnostic Excellence for Cancer

This Viewpoint discusses the need to expand early cancer detection to include both screening and symptom detection to achieve the goal of diagnostic excellence for cancer.

Incorrect Reference

In the US Preventive Services Task Force review titled “Screening for Impaired Visual Acuity in Older Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force,” published in the June 7, 2022, issue of JAMA, a reference was incorrect. Reference 10 should have appeared as “Evans JR, Lawrenson JG. Antioxidant vitamin...

Changes in Incidence of Stroke and Other Vascular Events at Younger vs Older Ages, 2002-2018

This study assesses time trends in incidence of stroke, transient ischemic attack, and other major vascular events at younger vs older ages in a population living in Oxfordshire, England, in 2002-2018.

Therapeutic Strategies for Intracranial Atherosclerosis

Intracranial atherosclerosis (ICAS) is a major cause of stroke worldwide. Although approximately 12% of White patients with a history of acute ischemic stroke or transient ischemic attack (TIA) have some form of ICAS detected on routine screening in predominantly older adults, ICAS accounts for an estimated up to one-third of ischemic strokes in Black,...

More Effective Flu Vaccines Recommended for Older Adults

Adults aged 65 years or older should receive high-dose or adjuvanted seasonal influenza vaccines, according to a new CDC recommendation.

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