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Latest Results for Annals of Nuclear Medicine

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Latest articles

Detectable size of melanoma metastases to brain on PET/CT

Abstract Objective We aimed to determine at what size melanoma metastases become detectable by PET/CT. Methods We reviewed a total of 293 whole-body PET/CT studies performed on 212 patients for staging...

Diagnostic utility and characteristics of CT-based attenuation correction in brain perfusion SPECT/CT in predicting the exacerbation of Alzheimer changes from mild cognitive impairment utilizing voxel-based statistical analysis in comparison with Chang’s method

Abstract Objective We examined the diagnostic value of brain perfusion single-photon emission computed tomography (SPECT) using voxel-based statistical analysis with CT-based attenuation correction (CT-AC) by comparing it to that with Chang’s AC in mild cognitive impairment (MCI) patients...

Applying Wells score to inconclusive perfusion only modified PIOPED II (Prospective Investigation of Pulmonary Embolism Diagnosis II) readings in order to optimize the lung scintigraphy diagnostic yield in acute pulmonary embolism detection

Abstract Objective When using perfusion only modified PIOPED II criteria for PE detection, generated non-diagnostic scans are found to be the main diagnostic restriction. The objective of current study is to identify the role of Wells criteria added to inconclusive readings with the intent...

Preoperative F-18 fluorocholine PET/CT for the detection of hyperfunctioning parathyroid glands in patients with secondary or tertiary hyperparathyroidism: comparison with Tc-99m sestamibi scan and neck ultrasound

Abstract Objectives Currently, neck ultrasound is the preferred preoperative imaging in patients with secondary/tertiary hyperparathyroidism, and the use of Tc-99m sestamibi scan is limited in these patients. We conducted this study to compare the diagnostic utilities of F-18 fluorocholine...

Physiological 18F-FDG uptake in the normal adult anal canal: evaluation by PET/CT

Abstract Objective Despite their benefit for detecting primary tumors, data for normal 18F-fluoro-2-deoxy-d-glucose (FDG) uptake in the anal canal are insufficient. Here we used positron emission tomography–computed tomography (PET/CT) to determine the uptake of FDG in the normal adult...

Effects of animal handling on striatal DAT availability in rats

Abstract Objective Positron emission tomography (PET) is a non-invasive technique measuring quantification of physiological and biochemical processes in the living organism. However, there are many considerations including anesthesia and fasting to acquire small animal imaging. We aimed...

Does bone scintigraphy still have a role in the era of 68 Ga-PSMA PET/CT in prostate cancer?

Abstract Objection We aimed to evaluate the role of bone scintigraphy (BS) which has long been the imaging modality of choice in prostate cancer (PCa) and performed a head-to-head comparison between BS, BS + SPECT/CT and 68 Ga-PSMA-PET/CT, for the detection of bone metastasis of PCa. ...

In vitro/in vivo assessment of the targeting ability of [ 99m Tc] Tc-labeled an aptide specific to the extra domain B of fibronectin (APT EDB ) for colorectal cancer

Abstract Objective The APTEDB is an aptide specific to the extra domain B (EDB) of fibronectin with high affinity for EDB, which is expressed in malignant tumors including brain cancer (U87MG) and colorectal cancer (HT-29). Aim of this study was to evaluate the [99mTc] Tc-APTEDB potential...

Synthesis and evaluation of novel radioiodinated anthranilate derivatives for in vivo imaging of vascular endothelial growth factor receptor with single-photon emission computed tomography

Abstract Objective Angiogenesis facilitates tumor survival and promotes malignancy. The vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR) tyrosine kinase (TK) signaling pathway is a key factor mediating angiogenesis, suggesting that this pathway may be a target for diagnosis...

Improvement in cognitive decline after indirect bypass surgery in adult moyamoya disease: implication of 15 O- gas positron emission tomography

Abstract Purpose To investigate the characteristics of patients with moyamoya disease (MMD) who show improvement in their cognitive decline after bypass surgery by analyzing the hemodynamic and metabolic parameters of 15O-gas positron emission tomography (PET). ...

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