Abstract Anti-PLA2R antibody is only expressed in podocytes from patients with idiopathic membranous nephropathy (IMN). The detection of anti-PLA2R antibody in serum is therefore able to obtain essential information for rapid diagnosis and evaluation of the disease activity of IMN. In the present study, a polydopamine nanosphere-based...

Abstract The fabrication of a highly sensitive DNA biosensor based on tin-doped WO3/In2O3 nanowires as heterojunction photoelectrode for detection of hepatitis B virus is reported. The tin-doped WO3/In2O3 nanowires were fabricated via a physical vapor deposition mechanism and were nearly 50 nm in width. The single-strand DNA probe...

Abstract An amperometric l-ascorbic acid biosensor utilizing ascorbate oxidase (AOx) immobilized onto poly(l-aspartic acid) (P(l-Asp)) film was fabricated on carbon nanofiber (CNF) and nanodiamond particle (ND)-modified glassy carbon electrode (GCE). Effects of AOx, ND, and CNF amounts were investigated by monitoring the response...

Abstract The use of stationary-phase optimized selectivity in liquid chromatography (SOS-LC) was shown to be successful for HPLC to analyze complex mixtures using a Phase OPtimized Liquid Chromatography (POPLC) kit. This commercial kit contains five stationary-phase types of varying lengths, which can be coupled to offer an improved...

Abstract Oligonucleotide therapeutics have contributed remarkably to healthcare, being well suited for the treatment of intractable diseases that are difficult to approach using conventional drug modalities. However, as common techniques of oligonucleotide analysis rely on reversed-phase or ion-exchange liquid chromatography and thus...