Integrating Low‐Temperature‐Resistant Two‐Dimensional Elastic‐Bending and Reconfigurable Plastic‐Twisting Deformations into an Organic Crystal

Integrating plasticity and elasticity is theoretically possible for anisotropic molecular crystals and it is beneficial to the rich and complex deformations, however, it is much harder to implement in practice. Here, we report a centimeter-long organic crystal that is two-dimensionally (2D) elastic-bendable not only at room temperature but also at ultralow...

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Expedient Synthesis of Ubiquitin‐like Protein ISG15 Tools Through Chemo‐Enzymatic Ligation Catalyzed by a Viral Protease Lbpro

Ubiquitin (Ub)-like protein ISG15 (interferon-stimulated gene 15) regulates innate immunity and is implicated in the evasion of the host response by viruses such as SARS-CoV-2. Dissecting ISGylation pathways recently received increasing attention which can illuminate the biological functions of ISG15 and inform related disease interventions, but such...

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The Crucial Role of Electrode Potential of a Working Anode in Dictating the Structural Evolution of Solid Electrolyte Interphase

The performance of rechargeable lithium (Li) batteries is highly correlated with the structure of solid electrolyte interphase (SEI), which governs the ion transport at the anode/electrolyte interface and directly impacts the cycle lifespan of the anode. The properties of a working anode are vital factors in determining the structure of SEI; however,...

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Electrochemical Conjugation of Aptamers on Carbon Fiber Microelectrode Enables Highly Stable and Selective In Vivo Neurosensing

Interfacing aptamers with carbon fiber microelectrodes (CFEs) provides a versatile platform to probe the chemical activity in living brain at the molecular level. However, new chemistries are needed for efficient and stable modifying aptamers on electrode surfaces. Here, we present an electrochemical conjugation strategy to covalent couple aptamers...

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Palladium‐Catalyzed Aryldifluoromethylation of Aryl Halides with Aryldifluoromethyl Trimethylsilanes

Diaryl difluoromethanes are valuable targets for medicinal chemistry because they are bioisosteres of diaryl ethers and can function as replacements for diaryl methane, ketone, and sulfone groups. However, methods to prepare diaryl difluoromethanes are scarce, especially methods starting from abundant aryl halides. We report the Pd-catalyzed aryldifluoromethylation...

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Modular Construction of Heterobiaryl Atropisomers and Axially Chiral Styrenes via All‐Carbon Tetrasubstituted VQMs

Here we report a new type of chiral all-carbon tetrasubstituted VQMs generated via chiral phosphoric acids catalyzed nucleophilic addition of 2-alkynylnaphthols to o -quinone methides or imines, which can be captured intramolecularly as a result of cycloaddition reaction. A new class of naphthyl-2 H -chromenes bearing axially and centrally chiral...

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Sorbents for Atmospheric Water Harvesting: from Design Principles to Applications

Water scarcity caused by climate change and population growth poses a grave threat to human society. Of the different water purification technologies put forward, one presents a promising strategy that is spatially or temporally non-restricted – atmospheric water harvesting (AWH). Here we review recent progress in the designs and studies of AWH sorbents,...

1d

Metal‐Chelatable Porphyrinic Frameworks for Single‐Cell Multiplexing with Mass Cytometry

A new design strategy for mass cytometry markers is reported using functionalized mesoporous porphyrinic frameworks (MPF) as scaffolds for chelating metals that have been difficult to integrate in conventional markers. With polyethylene glycol surface functionalization, post-synthetic metalation and antibody conjugation, the resulting MPF-based markers...

3d

A Self‐Assembled Cage Binding Iodide Anions over Other Halide Ions in Water

A macrocycle M 4+ and a cage C 6+ were self-assembled by hydrazone formation in acidic aqueous solution. The cage is capable of encapsulating I− selectively over other halide anions in water; the macrocycle does not exhibit any recognition towards these other anions. Abstract A triangular-prism shaped cage was self-assembled by the formation...

3d

Hydrogen Spillover and Its Relation to Hydrogenation: Observations on Structurally Defined Single‐Atom Sites

Ein Pd-Einzelatomkatalysator wird im Forschungsartikel (DOI: 10.1002/ange.202208237) von Ning Yan und Mitarbeitern genutzt, um die Kinetik und die strukturelle Entwicklung von Katalysatoren im Wasserstoff-Spillover sowie die Beteiligung des Spillover-Wasserstoffs an Hydrierungen zu untersuchen.

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