Divergent Construction of Diverse Scaffolds via Catalyst‐controlled C−H Activation Cascades of Quinazolinones and Cyclopropenones

A transition-metal catalyzed C−H activation cascade strategy to rapidly construct diverse quinazolinone derivatives in a one-pot manner is reported. The catalysts play an important role in the different transformations. Additionally, the procedure is scalable, proceeds with high efficiency and good chemo-/regio-selectivity, and tolerates a range of...

7h

Osmaindenes: Synthesis and Reversible Mechanochromism Characteristics

A series of novel osmaindenes 1 – 6 bearing different substituents (CF 3 , H, I, Br, OCH 3 , N(Ph) 2 ) has been synthesized by nucleophilic reaction of water with the corresponding aromatic osmanaphthalyne complexes. All osmaindenes 1 – 6 have been characterized by elemental analysis (EA) and nuclear magnetic resonance (NMR) spectroscopy,...

7h

The stereoselective oxidation of para‐substituted benzenes by a cytochrome P450 biocatalyst.

The serine 244 to aspartate (S244D) variant of the cytochrome P450 enzyme CYP199A4 was used to expand its substrate range beyond benzoic acids. Substrates, in which the carboxylate group of the benzoic acid moiety is replaced, were oxidised with high activity by the S244D mutant (product formation rates > 60 nmol.(nmol-CYP) −1 .min −1 ) and with...

7h

Large Isotope Effects in Organometallic Chemistry

The kinetic isotope effect (KIE) is key to understanding reaction mechanisms in many areas of chemistry and chemical biology, including organometallic chemistry. This ratio of rate constants, k H / k D , typically falls between 1-7. However, KIEs up to 105 have been reported, and can even be so large that reactivity with deuterium is unobserved....

7h

Rational Fabrication of Multiple Dimensional Assemblies from Tryptophan‐Based Racemate

Fabricating structural complex assemblies from simple amino acid-based derivatives is attracting great research interests due to their easy accessibility and preparation. However, the morphological regulation of racemates (an equimolar mixture of enantiomers) were largely overlooked. In this work, through rational modulation of kinetic and thermodynamic...

7h

Hexaphenylditetrels – When Longer Bonds Provide Higher Stability

We present a computational analysis of hexaphenylethane derivatives with heavier tetrels comprising the central bond. In stark contrast to parent hexaphenylethane, the heavier tetrel derivatives can readily be prepared. In order to determine the origin of their apparent thermodynamic stability against dissociation as compared to the carbon case, we...

7h

Engineering Functional Interface with Built‐in Catalytic and Self‐oxidation Sites for Highly Stable Lithium Sulfur Battery

Lithium sulfur (Li-S) battery has attracted great attention due to its high theoretical energy density. The rapid redox conversion of lithium polysulfides (LiPS) is effective for solving the serious shuttle effect and improving utilization of active materials. The functional design of separator interface with the fast charge transfer and active catalytic...

1d

Graphene Oxide‐Assisted Covalent Triazine Framework for Boosting Photocatalytic H2 Evolution

The π-conjugation-linked CTF-1/GO hybrid material fabricated by facile low-temperature condensation of 1,4-dicyanobenzene in the presence of graphene oxide (GO) exhibited an optimum H2 evolution rate of 2262.4 μmol g−1 ⋅ h−1 under visible light irradiation, which was 9 times that of pure CTF-1. This result indicates addition of certain additives, particularly...

1d

Hexaphenylditetrels – When Longer Bonds Provide Higher Stability

We present a computational analysis of hexaphenylethane derivatives with heavier tetrels comprising the central bond. In stark contrast to parent hexaphenylethane, the heavier tetrel derivatives can readily be prepared. In order to determine the origin of their apparent thermodynamic stability against dissociation as compared to the carbon case, we...

1d

Sequential Hydrogen Tunneling in o‐Tolylmethylene

o -Tolylmethylene 1 is a metastable triplet carbene that rearranges to o -xylylene 2 even at temperatures as low as 2.7 K via [1,4] H atom tunneling. Electron paramagnetic resonance (EPR) and electron nuclear double resonance (ENDOR) spectroscopical techniques were used to identify two conformers of 1 ( anti and syn ) in noble gas matrices...

1d