While pathologic staging is considered the gold standard in head and neck cancers, clinical staging guides initial treatment plans and patient counseling. This study aims to identify specific stages and primary tumor subsites where discordance between clinical and pathologic staging is high. We found that T2 Oral Cavity, T2 Oropharynx, T3 Larynx,...

Research participant samples that are representative of the patient population are needed to ensure appropriate interpretation and application of research findings for all patients. We evaluated the efficacy of a specific study design and recruitment strategy in obtaining a participant sample that was representative of the cochlear implant patient...

We describe a case of acute invasive fungal sinusitis (AIFS) in an immunocompetent, non-diabetic patient after endoscopic sinus surgery. The patient presented with retro-orbital pain progressing to vision loss and was treated with surgical debridement, systemic antifungal therapy, and transcutaneous retro-bulbar injection of amphotericin B resulting...

In the current investigation, the application of alpha1-antitrypsin (AAT) to mice with acute tympanic membrane perforation accelerated the healing process, leading to earlier expression of growth factors such as VEGF, TGFβ, and collagen-5A1. AAT also increased IL-10 expression levels and decreased IL-6 levels in the treated mice. These findings suggest...

Few validated risk prediction models in head and neck cancer exist for length of stay after surgery. Comparison of ACS-NSQIP calculator, machine learning, and statistical models for length of stay was made. All models were superior to ACS-NSQIP with fair performance. Machine learning model slightly outperformed all other models. Creatinine, surgery...

A 47-year-old male patient diagnosed with severe obstructive sleep apnea (OSA) sought alternatives to positive airway pressure, prompting evaluation with drug-induced sleep endoscopy (DISE). He underwent a specialized DISE with nasal airflow and pharyngeal pressure monitoring. During obstructive apneas, airflow and pressure signals demonstrated dynamic,...