This study reports an integrated platform for simultaneous modulation and monitoring of cardiomyocyte function in vitro. Optical inputs are achieved through expression of a photoactivatable adenylyl cyclase, that when irradiated causes a reversible increase in beating rate. Bioelectronic outputs are achieved with a multi-electrode array, which can...

Natural deep eutectic solvent-exfoliated silk nanofibers with highly intact natural hierarchical structure can effectively assist liquid-phase exfoliation of 2D materials via hydrogen bonding and hydrophobic–hydrophobic interactions. The formed dispersion of silk nanofiber and boron nitride nanosheet can self-assembly into nanocomposite membranes...

This study identified SHISA3 as a valuable therapeutic gene for cancer immunotherapy. Higher expression of SHISA3 in TAMs is associated with better overall survival in lung cancer patients. Enforced expression of Shisa3 in TAMs enables cancer immunotherapy by NF-κB-mediated reprogramming of TAMs toward an antitumoral phenotype, thus enhances the efficacy...

Through assembling the Fe3 cluster and the organic dye 4,4′,4″- Nitrilotrisbenzoic acid in a metal–organic framework material, Fe3-MOF. After parallel photoexcitation of Fe3-MOF, Cl•, and O2 •− are produced for functionalizing C(sp 3)─H bonds. It represents the first example of coordination polymer to accelerate C(sp 3)─H bonds functionalization...

An analytical model for the transient response of organic electrochemical transistors combines vertical ionic diffusion and horizontal electronic transport. A classification of transients and hysteresis effects is obtained, and the model is developed by experimental measurements and advanced simulations. Abstract The switching response in...

This work presents a systematic nature-inspired chemical engineering methodology to facilitate the design of flow fields for hydrogen fuel cells. Inspired by the passive water transport mechanism observed in desert lizards’ integument, a scalable water management strategy is devised. This approach significantly enhances water removal, uniformizes...