Wiley Online Library : Journal of Clinical Pharmacy and Therapeutics
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Thu Dec 22, 2022 07:45
Tumour necrosis factor inhibitor combined with intravenous immunoglobulin and heparin for treatment of recurrent spontaneous abortion: A two‐centre, retrospective, cohort study

A total of 105 recurrent spontaneous abortion (RSA) patients who received tumour necrosis factor inhibitor (TNFi) + intravenous immunoglobin (IVIG) + Heparin (enoxaparin) (n = 48) or IVIG+Heparin (enoxaparin) (n = 57) were retrospectively included in this two-centre cohort study. Live birth rate was increased in the TNFi+IVIG+Heparin group compared...

Tue Dec 13, 2022 16:22
Extended‐release naltrexone for people with alcohol use disorder on therapeutic anticoagulation: A case series

Guide to XR-NTX Discussion for Patients on Therapeutic Anticoagulation. Abstract What is known and objective Individuals with medication adherence challenges or a preference for long-acting medications may benefit from extended-release naltrexone (XR-NTX) for treatment of alcohol use disorder (AUD). Individuals on therapeutic anticoagulation...

Tue Dec 13, 2022 16:22
Impact of mulberry consumption on cardiometabolic risk factors: A systematic review and meta‐analysis of randomized‐controlled trials

The current study aimed to comprehensively evaluate the potential effects of mulberry consumption on cardio metabolic risk factors in adults. The current systematic review and meta-analysis revealed that incorporating mulberry into the diet may favourably affect several cardio metabolic risk factors. Consumption > 300 mg/day of mulberry exhibited...

Tue Dec 13, 2022 11:24
Efficacy and safety of camrelizumab plus apatinib compared to apatinib monotherapy as third‐line or above therapy for metastatic colorectal cancer patients: A retrospective cohort study

This study aimed to investigate the treatment efficacy and safety of camrelizumab (programmed cell death protein-1 (PD-1) inhibitor) plus apatinib as third-line or above therapy in metastatic colorectal cancer (mCRC) patients. Totally, 64 unresectable mCRC patients receiving camrelizumab plus apatinib (N = 31) and apatinib (N = 33) were retrospectively...

Sun Dec 11, 2022 10:34
Pharmacokinetic/pharmacodynamic analysis of high‐dose tigecycline, by Monte Carlo simulation, in plasma and sputum of patients with hospital‐acquired pneumonia

The study collected 108 blood specimens and60 sputum specimens from 12 enrolled patients Subsequently, these specimens were assayedfor tigecycline drug concentrations by high-performance liquid chromatography (HPLC).The relevant pharmacokinetic (PK) parameters were estimated by the non-compartmental model usingWinNonlin software. And Crystal Ball...

Thu Dec 8, 2022 11:16

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