Journal of Pharmacy and Pharmacology
Abstract Objectives As a traditional Chinese medicine, lotus leaf was reported to have significant hepatoprotective effect. To explore the hepatoprotective mechanism of lotus leaf, a rapid and reliable UPLC‐MS/MS method was conducted to simultaneously determine six specific endogenous substances including 5‐oxoproline, phenylalanine, tryptophan,...
Abstract Objectives Umbelliprenin (UMB) is a prenylated coumarin that acts as an in vitro antioxidant and inhibits lipoxygenase managing the inflammation pathways, while in vivo it exerts anti‐inflammatory activities. Methods In this study, neuropathic pain was induced by four intraperitoneal doses of 2 mg/kg per day of paclitaxel (PTX) on...
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