Cell RSS feed. For more than 30 years, top international researchers have relied on Cell to publish high impact papers that have come to form the foundation of contemporary life science research. Founded by Benjamin Lewin (author of Genes), Cell rem
Brouwer et al. present preclinical evidence in support of a COVID-19 vaccine candidate, designed as a self-assembling two-component protein nanoparticle displaying multiple copies of the SARS-CoV-2 spike protein, which induces strong neutralizing antibody responses and protects from high-dose SARS-CoV-2 challenge.
Distinct from their contributions to stress granules, G3BPs regulate mTORC1 activity through spatial control of the TSC complex.
Tan et al. show that during development, both the transcriptome and 3D genome are extensively transformed in the first post-natal month independent of sensory experience, suggesting that the 3D transformation is predetermined.
Darkness-induced melatonin signaling modulates the proliferative state of neural stem cells through the modulation of Ca2+ dynamics as evidenced by live imaging and optogenetically induced “quiescent-state”-like calcium patterns in freely behaving mice.
C9orf72 mutations associated with ALS and FTD activate a specific transcriptional program that converges on p53 to drive neurodegeneration in multiple C9orf72 models.
Cell-cycle-dependent recombinase-like activity of EBNA1 is required for replication termination and viral episome maintenance of oncogenic Epstein-Barr virus.
Previous intestinal infection increases the gut microbiota’s resistance to subsequent infection by inhibiting the ability of pathogens to respire.
Food allergy may be a harmful manifestation of a normal food quality control mechanism.
Spliceosome-targeted therapies generate intron-retained, double-stranded RNAs that activate downstream antiviral signaling and extrinsic apoptosis in breast cancer.
Wang et al. show atopic dermatitis-associated inflammation promotes a basophil-leukotriene neuroimmune axis to evoke acute itch flares.
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