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A systematic review and meta-analysis of diagnostic performance of fluorescein-guided sentinel lymph node biopsy in early breast cancer

ConclusionFluorescein-guided SLNB is a viable option for detection of lymph node metastases in clinically node negative patients with early breast cancer. It achieves a high pooled Sentinel Lymph Node Identification Rate (SLN-IR) of 93% with a false negative rate of 5.6% for the detection of axillary lymph node metastasis. (Source: Breast Cancer Research...

Sat Apr 27, 2024 12:12
Unveiling the potential of breast MRI: a game changer for BI-RADS 4A microcalcifications

ConclusionsBreast MRI has the potential to improve the diagnosis of BI-RADS 4A microcalcifications on mammography. We propose a potential clinical pathway that patients with BI-RADS 4A on mammography who are premenopausal, have no personal history of breast cancer (family history) or have non-clustered distribution of calcifications can undergo MRI...

Sat Apr 27, 2024 12:12
Indocyanine green angiography guidance for vascular preservation in skin and nipple sparing mastectomy

ConclusionThis prospective study using preoperative ICG perfusion mapping demonstrated safety, feasibility, and good prognostic outcomes.Level of evidenceIII. (Source: Breast Cancer Research and Treatment)

Fri Apr 26, 2024 08:20
Perspectives on shorter durations of anti-HER2 therapy in early-stage HER2-positive breast cancer: a patient survey

ConclusionTrials to investigate who can safely and effectively be treated with shorter durations of anti-HER2 therapy are needed. This study provides important insights to patients ’ perspectives on shorter durations of anti-HER2 treatment, and their concerns regarding potential increased cancer risk with less treatment. (Source: Breast Cancer Research...

Fri Apr 26, 2024 08:20
Characteristics and risk factors of axillary lymph node metastasis of microinvasive breast cancer

ConclusionLow ALNM rate (4.1%) suggests that routine SLNB for patients with MIBC is unnecessary but  can be valuable for patients with specific risk factors. Ongoing trials for omitting SLNB in early breast cancer, and further subanalyses focusing on rare populations with MIBC are necessary. (Source: Breast Cancer Research and Treatment)

Fri Apr 26, 2024 08:20
Impact of HER2 status on clinicopathological characteristics and pathological complete response to neoadjuvant chemotherapy in triple-negative breast cancer

ConclusionsIn our cohort, HER2-low TNBC patients exhibits specific clinical characteristics and response features to NAC. (Source: Breast Cancer Research and Treatment)

Thu Apr 25, 2024 16:25

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