Coronapod: CureVac disappoints in COVID vaccine trial

Nature, Published online: 11 June 2021; doi:10.1038/d41586-021-01694-5Scientists are asking why the third mRNA vaccine may have fallen at the last hurdle

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CureVac COVID vaccine let-down spotlights mRNA design challenges

Nature, Published online: 18 June 2021; doi:10.1038/d41586-021-01661-0Scientists are searching for explanations to disappointing final-stage trial results. These insights could help guide the future development of mRNA vaccines.

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Base editor treats progeria in mice

Nature, Published online: 18 June 2021; doi:10.1038/d41586-021-01114-8A single dose of an adenine base editor shows promise in treating the ageing-related disease Hutchinson–Gilford progeria syndrome. It corrected the LMNA mutation underlying the disease in patient-derived cells and improved cardiovascular health and lifespan in mice.

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Towards personalized treatment of smoking-related lung cancers

Nature, Published online: 18 June 2021; doi:10.1038/d41586-021-01113-9An innovative approach to a phase II clinical trial aims to test the effects of multiple targeted treatments simultaneously in participants in the UK National Lung Matrix Trial. The design makes it possible to study small numbers of people with rare mutations in non-small-cell lung...

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Mathematicians welcome computer-assisted proof in ‘grand unification’ theory

Nature, Published online: 18 June 2021; doi:10.1038/d41586-021-01627-2Proof-assistant software handles an abstract concept at the cutting edge of research, revealing a bigger role for software in mathematics.

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Author Correction: Assembly of synaptic active zones requires phase separation of scaffold molecules

Nature, Published online: 18 June 2021; doi:10.1038/s41586-021-03340-6Author Correction: Assembly of synaptic active zones requires phase separation of scaffold molecules

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Better together: collaborative spaces can inspire scientists of all ages

Nature, Published online: 18 June 2021; doi:10.1038/d41586-021-01658-9An area where researchers can gather and informally discuss ideas is the best way to produce innovative inventions, argues Ethan N. Gotian.

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How scientists are embracing NFTs

Nature, Published online: 18 June 2021; doi:10.1038/d41586-021-01642-3Is a trend of auctioning non-fungible tokens based on scientific data a fascinating art fad, an environmental disaster or the future of monetized genomics?

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Daily briefing: Why humans are so thirsty

Nature, Published online: 17 June 2021; doi:10.1038/d41586-021-01657-wWhy humans need to drink more water than most mammals, why dust clouds follow the Mars helicopter and disappointing news from trials of the CureVac COVID-19 vaccine.

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Communities, COVID and credit: the state of science collaborations

Nature, Published online: 17 June 2021; doi:10.1038/d41586-021-01652-1The pros and pitfalls of partnering in science, with insights from researchers and beyond.

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