Nature Biotechnology - Issue - nature.com science feeds

Nature Biotechnology journal featuring biotechnology articles and science research papers of commercial interest in pharmaceutical, medical, and environmental sciences.

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Maintaining ‘standards’ for biosimilar monoclonal antibodies

Nature Biotechnology, Published online: 04 March 2021; doi:10.1038/s41587-021-00848-0Maintaining ‘standards’ for biosimilar monoclonal antibodies

Author Correction: ChIP-seq of plasma cell-free nucleosomes identifies gene expression programs of the cells of origin

Nature Biotechnology, Published online: 01 March 2021; doi:10.1038/s41587-021-00853-3Author Correction: ChIP-seq of plasma cell-free nucleosomes identifies gene expression programs of the cells of origin

Publisher Correction: Light-activated genetic therapy to treat blindness enters clinic

Nature Biotechnology, Published online: 01 March 2021; doi:10.1038/s41587-021-00871-1Publisher Correction: Light-activated genetic therapy to treat blindness enters clinic

Affinity-matured HLA class II dimers for robust staining of antigen-specific CD4<sup>+</sup> T cells

Nature Biotechnology, Published online: 01 March 2021; doi:10.1038/s41587-021-00836-4CD4+ T cells are readily detected with class II MHC dimers.

The missing sex

Nature Biotechnology, Published online: 23 February 2021; doi:10.1038/s41587-021-00844-4For most of its history, biomedical research and clinical testing has neglected over half of the world’s population. Finally, researchers and funders are starting to recognize the importance of sex differences.

Biological activity-based modeling identifies antiviral leads against SARS-CoV-2

Nature Biotechnology, Published online: 23 February 2021; doi:10.1038/s41587-021-00839-1Activity profiles generated from quantitative high-throughput screening improve drug candidate prediction.

Mapping innovation trajectories on SARS-CoV-2 and its variants

Nature Biotechnology, Published online: 22 February 2021; doi:10.1038/s41587-021-00849-zMapping innovation trajectories on SARS-CoV-2 and its variants

Variability within rare cell states enables multiple paths toward drug resistance

Nature Biotechnology, Published online: 22 February 2021; doi:10.1038/s41587-021-00837-3A new methodology, Rewind, traces vemurafenib-resistant melanoma back to its initial cell state before drug treatment, creating, effectively, a cellular time machine.

Could mutations of SARS-CoV-2 suppress diagnostic detection?

Nature Biotechnology, Published online: 18 February 2021; doi:10.1038/s41587-021-00845-3Could mutations of SARS-CoV-2 suppress diagnostic detection?

Robust decomposition of cell type mixtures in spatial transcriptomics

Nature Biotechnology, Published online: 18 February 2021; doi:10.1038/s41587-021-00830-wCell type mapping in spatial transcriptomics is enabled by accounting for compositional mixtures and differences in sequencing technologies.

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