Nature Chemistry

Nature Chemistry is a unique forum for chemists of all disciplines. Every month Nature Chemistry publishes original top-quality research, plus a compelling mix of news and reviews, in print and online.

Latest articles

Connecting remote C–H bond functionalization and decarboxylative coupling using simple amines

Nature Chemistry, Published online: 09 March 2020; doi:10.1038/s41557-020-0428-1A catalytic para-selective alkylation reaction connects C–H functionalization and decarboxylative coupling strategies using simple bases to trap a previously hidden intermediate. This reaction exploits an ‘inverted sequence’ that forms the C–C bond prior to C–H bond cleavage...

A programmable polymer library that enables the construction of stimuli-responsive nanocarriers containing logic gates

Nature Chemistry, Published online: 09 March 2020; doi:10.1038/s41557-020-0426-3A programmable polymer library that responds to external and internal stimuli has been developed and used to fabricate a series of nanocarriers for drug release. The carriers respond to disease biomarkers, triggering self-immolative motifs and leading to the site-specific...

Vibrational coherences in manganese single-molecule magnets after ultrafast photoexcitation

Nature Chemistry, Published online: 02 March 2020; doi:10.1038/s41557-020-0431-6Controlling single-molecule magnets (SMMs) with ultrashort laser pulses could be key to future data storage devices, however, the photophysics of SMMs is complex. Now, using a monomer model system, it has been shown that optical excitation of Mn(iii)-SMMs leads to a modulation...

Heteromeric three-stranded coiled coils designed using a Pb(<span class="small-caps">ii</span>)(Cys)<sub>3</sub> template mediated strategy

Nature Chemistry, Published online: 02 March 2020; doi:10.1038/s41557-020-0423-6A method to fabricate heterotrimeric three-stranded coiled-coil peptide structures has now been developed using coordination around a Pb(ii) centre. The heterotrimeric structures require only three cysteines that bind to Pb(ii) to form a trigonal pyramidal structure, and...

Differentiation and functionalization of remote C–H bonds in adjacent positions

Nature Chemistry, Published online: 02 March 2020; doi:10.1038/s41557-020-0424-5Distinguishing remote C–H bonds on adjacent carbon atoms is a fundamental challenge because of a lack of electronic or steric bias. Now, differentiation of distal C–H bonds that are adjacent to each other has been achieved by combining selective remote C–H activation—based...

Odd–even alternations in helical propensity of a homologous series of hydrocarbons

Nature Chemistry, Published online: 02 March 2020; doi:10.1038/s41557-020-0429-0Even- and odd-numbered homologues of some hydrocarbons are known to exhibit different trends in solid-state properties. Now, experimental and computational investigations on a homologous series of a stereochemically well-defined hydrocarbon have revealed an odd–even effect...

Spatial separation of triplet excitons drives endothermic singlet fission

Nature Chemistry, Published online: 02 March 2020; doi:10.1038/s41557-020-0422-7Generating high-energy triplet excitons from singlet fission without excess energy loss is a critical goal for potential applications. Now it is shown that molecular chromophores that are connected covalently can harbour multiple long-lived and high-energy triplets—created...

Heavy metal orchestration

Nature Chemistry, Published online: 27 February 2020; doi:10.1038/s41557-020-0434-3Many current methods to prepare 2-hydroxybiaryls require the prefunctionalization of phenol groups or show limited substrate scope. Now, use of a pentavalent sulfone-bridged bismacycle, formed in situ by telescoped boron-to-bismuth transmetallation and oxidation, allows...

Modular bismacycles for the selective C–H arylation of phenols and naphthols

Nature Chemistry, Published online: 27 February 2020; doi:10.1038/s41557-020-0425-4Step-economic access to the biologically relevant 2-hydroxybiaryl motif represents a long-standing challenge in synthetic organic chemistry. Now, a bismuth-mediated oxidative arylation of phenols and naphthols with boronic acids has been developed — supported by experimental...

RNA returns to the fold

Nature Chemistry, Published online: 27 February 2020; doi:10.1038/s41557-020-0432-5RNA has multiple roles in biology, enabled by its structural diversity. Now, artificially grafted RNA motifs have been encoded in a single RNA strand to form self-assembling nanostructures with controlled geometry and function.

Discover, share and read the best on the web

Subscribe to RSS Feeds, Blogs, Podcasts, Twitter searches, Facebook pages, even Email Newsletters! Get unfiltered news feeds or filter them to your liking.

Get Inoreader
Inoreader - Subscribe to RSS Feeds, Blogs, Podcasts, Twitter searches, Facebook pages, even Email Newsletters!