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Nature Communications is an online-only, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, physical and chemical sciences. Papers published by the journal represent important advances of significa

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On-chip integrated process-programmable sub-10 nm thick molecular devices switching between photomultiplication and memristive behaviour

Nature Communications, Published online: 24 May 2022; doi:10.1038/s41467-022-30498-yDeveloping molecular electronics is challenged by integrating fragile organic molecules into modern micro/nanoelectronics based on inorganic semiconductors. Li et al. apply rolled-up nanotechnology to assemble on-chip molecular devices, which can be switched between...

Ring walking as a regioselectivity control element in Pd-catalyzed C-N cross-coupling

Nature Communications, Published online: 24 May 2022; doi:10.1038/s41467-022-30255-1The phenomenon of „ring-walking‟, wherein a metal catalyst remains bound to a pi system as it migrates to another coupling site, is supported largely by circumstantial evidence. Here the authors perform an in-depth kinetic study of Buchwald- Hartwig animations with several...

Addressing the socioeconomic divide in computational modeling for infectious diseases

Nature Communications, Published online: 24 May 2022; doi:10.1038/s41467-022-30688-8The COVID-19 pandemic has highlighted how structural social inequities fundamentally shape disease dynamics. Here, the authors provide a set of practical and methodological recommendations to address socioeconomic vulnerabilities in epidemic models.

Competent immune responses to SARS-CoV-2 variants in older adults following two doses of mRNA vaccination

Nature Communications, Published online: 24 May 2022; doi:10.1038/s41467-022-30617-9mRNA-based SARS-CoV-2 vaccines can induce protective immunity in older individuals, but whether they encompass new variants is not clear. Here the authors assess mRNA vaccine responses in both younger (55) cohorts to find slightly delayed humoral and cellular immunity...

Exceptional parallelisms characterize the evolutionary transition to live birth in phrynosomatid lizards

Nature Communications, Published online: 24 May 2022; doi:10.1038/s41467-022-30535-wThere have been five independent transitions from egg laying to live birth in the phrynosomatid lizards. Here, Domínguez-Guerrero et al. identify parallel changes in physiology, life history and behaviour that characterize these transitions to live birth.

Auditory processing remains sensitive to environmental experience during adolescence in a rodent model

Nature Communications, Published online: 24 May 2022; doi:10.1038/s41467-022-30455-9Anbuhl et al. identify adolescence as a time of vulnerability to sensory deprivation. They find that even a transient loss of auditory experience causes long-lasting perceptual deficits that originate, in part, from a cortical processing deficit.

Functional expression of opioid receptors and other human GPCRs in yeast engineered to produce human sterols

Nature Communications, Published online: 24 May 2022; doi:10.1038/s41467-022-30570-7The yeast Saccharomyces cerevisiae is powerful for studying human G protein-coupled receptors as they can be coupled to its mating pathway. Here the authors engineer baker’s yeast to produce human sterols and show that vertebrate G protein coupled receptors are more...

Robust temporal map of human in vitro myelopoiesis using single-cell genomics

Nature Communications, Published online: 24 May 2022; doi:10.1038/s41467-022-30557-4The myeloid lineage is central to homeostasis and immunity. The authors provide an atlas of human iPSC-to-myeloid cell differentiation and demonstrate that the in vitro system recapitulates yolk sac differentiation, opening new avenues to human myelopoiesis.

Author Correction: A cattle graph genome incorporating global breed diversity

Nature Communications, Published online: 23 May 2022; doi:10.1038/s41467-022-30372-xAuthor Correction: A cattle graph genome incorporating global breed diversity

Origins of direction selectivity in the primate retina

Nature Communications, Published online: 23 May 2022; doi:10.1038/s41467-022-30405-5Neural coding for motion direction has been studied intensively in the visual cortex of non-human primates. Here, the authors establish an origin for direction selectivity in the retina of the macaque monkey.

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