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Nature Communications is an online-only, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, physical and chemical sciences. Papers published by the journal represent important advances of significa

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High-yield, wafer-scale fabrication of ultralow-loss, dispersion-engineered silicon nitride photonic circuits

Nature Communications, Published online: 16 April 2021; doi:10.1038/s41467-021-21973-zFor widespread technological application of nonlinear photonic integrated circuits, ultralow optical losses and high fabrication throughput are required. Here, the authors present a CMOS fabrication technique that realizes integrate photonic microresonators on waver-level...

Nanoscale magnonic Fabry-Pérot resonator for low-loss spin-wave manipulation

Nature Communications, Published online: 16 April 2021; doi:10.1038/s41467-021-22520-6Compared to electromagnetic waves, the wavelength of spin waves is significantly shorter at gigahertz frequencies, enabling the miniaturisation of wave-based devices. Here, the authors present a magnonic Fabry-Pérot resonator allowing for nanoscale and reconfigurable...

Detecting protein and DNA/RNA structures in cryo-EM maps of intermediate resolution using deep learning

Nature Communications, Published online: 16 April 2021; doi:10.1038/s41467-021-22577-3It is challenging to extract structural information from EM density maps at intermediate or low resolutions. Here, the authors present Emap2sec+, a program for detecting nucleotides and protein secondary structures in EM density maps at 5 to 10 Å resolution.

DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death

Nature Communications, Published online: 16 April 2021; doi:10.1038/s41467-021-22638-7Chemoresistance is one of the main challenges for cancer therapy success. Here, the authors show that dual-specificity phosphatase 16 (DUSP16) expression is associated with chemoresistance in several types of cancer through impairing mitochondria-associated apoptosis.

Hypothalamic Rax<sup>+</sup> tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice

Nature Communications, Published online: 16 April 2021; doi:10.1038/s41467-021-22640-zTanycytes contribute to the regulation of multiple hypothalamic functions. Here the authors investigate the regenerative and tumorigenic potential of adult Rax+ tanycytes in the median eminence in the context of the stem cell niche in mice.

Defective viral genomes as therapeutic interfering particles against flavivirus infection in mammalian and mosquito hosts

Nature Communications, Published online: 16 April 2021; doi:10.1038/s41467-021-22341-7Defective viral genomes (DVGs) can interfere with virus replication and provide a potential approach to control infection. Here, Rezelj et al. use a combined experimental evolution and computational approach to identify DVG sequences that optimally interfere with Zika...

A committed fourfold increase in ocean oxygen loss

Nature Communications, Published online: 16 April 2021; doi:10.1038/s41467-021-22584-4Ocean warming and changing circulation as a result of climate change are driving down oxygen levels and threatening ecosystems. Here the author shows that though immediate cessation of anthropogenic CO2 emissions would halt upper ocean oxygen loss, it would continue...

Classical MHC expression by DP thymocytes impairs the selection of non-classical MHC restricted innate-like T cells

Nature Communications, Published online: 16 April 2021; doi:10.1038/s41467-021-22589-zConventional T cell subsets are selected in the thymus by peptide bearing MHC expressed by cortical epithelial cells, in contrast cortical thymocytes express non-peptide bearing MHC molecules including CD1d and MR1 and select iNKT and MAIT cell populations respectively....

Author Correction: A model for the fragmentation kinetics of crumpled thin sheets

Nature Communications, Published online: 15 April 2021; doi:10.1038/s41467-021-22791-zAuthor Correction: A model for the fragmentation kinetics of crumpled thin sheets

Publisher Correction: A single-dose mRNA vaccine provides a long-term protection for hACE2 transgenic mice from SARS-CoV-2

Nature Communications, Published online: 15 April 2021; doi:10.1038/s41467-021-22820-xPublisher Correction: A single-dose mRNA vaccine provides a long-term protection for hACE2 transgenic mice from SARS-CoV-2

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