Author Correction: Structural dynamics of AAA + ATPase Drg1 and mechanism of benzo-diazaborine inhibition

Nature Communications, Published online: 27 January 2023; doi:10.1038/s41467-023-36072-4Author Correction: Structural dynamics of AAA + ATPase Drg1 and mechanism of benzo-diazaborine inhibition

14h

Estimation and implications of the genetic architecture of fasting and non-fasting blood glucose

Nature Communications, Published online: 27 January 2023; doi:10.1038/s41467-023-36013-1Most genetic studies of glucose levels have been done on fasting samples, which can be difficult to obtain. Here, the authors identify 156 genetic loci controlling the physiological variation of glucose levels in healthy non-fasting individuals, demonstrating that...

14h

Chromatin complex dependencies reveal targeting opportunities in leukemia

Nature Communications, Published online: 27 January 2023; doi:10.1038/s41467-023-36150-7Epigenetic regulators are potential therapeutic drug targets in leukemia. Here, the authors perform combinatorial CRISPR knockouts to test gene-gene pairings in leukemia cells to discover compensatory non-lethal or synergistic lethal combinations with therapeutic...

16h

Fundamental energy cost of finite-time parallelizable computing

Nature Communications, Published online: 27 January 2023; doi:10.1038/s41467-023-36020-2Based on fundamental thermodynamics, traditional electronic computers, which operate serially, require more energy per computation the faster they operate. Here, the authors show that the energy cost per operation of a parallel computer can be kept very small.

16h

Accelerating ultrafast magnetization reversal by non-local spin transfer

Nature Communications, Published online: 27 January 2023; doi:10.1038/s41467-023-36164-1Under laser illumination it is possible to drive a ferromagnet to lose its magnetization. While this process can be rapid, remagnetization following this is slower, due to the universal critical slowing down near the phase transition. Here, Remy et al show how such...

17h

Redox-dependent Igfbp2 signaling controls Brca1 DNA damage response to govern neural stem cell fate

Nature Communications, Published online: 27 January 2023; doi:10.1038/s41467-023-36174-zHow reactive oxygen species regulate neuronal stem cell (NSC) behavior is poorly understood. Here, the authors report that Ncf1-dependent oxidation of Igfbp2 cystines represses DNA repair networks to regulate NSC self-renewal and cell fate decisions.

17h

Liquid-liquid phase separation in supercooled water from ultrafast heating of low-density amorphous ice

Nature Communications, Published online: 27 January 2023; doi:10.1038/s41467-023-36091-1Obtaining experimental evidence of a liquid-liquid phase transition in supercooled water is challenging due to the rapid crystallization. Here the authors drive low-density amorphous ice to the conditions of liquid-liquid coexistence using ultrafast laser heating...

17h

Self-evolving photonic crystals for ultrafast photonics

Nature Communications, Published online: 27 January 2023; doi:10.1038/s41467-022-35599-2Generation and control of short pulse is desired for ultrafast applications. Here the authors demonstrate ultrafast pulse generation using self-evolving photonic crystal that can transition from high loss to low loss state based on dynamic dispersion compensation.

19h

Cellular senescence in malignant cells promotes tumor progression in mouse and patient Glioblastoma

Nature Communications, Published online: 27 January 2023; doi:10.1038/s41467-023-36124-9Senescence can have beneficial and detrimental impact on cancer progression depending on the cellular context. Here the authors show that NRF2 regulates the senescence phenotype in malignant cells which consequently contribute to glioblastoma progression.

20h

Epigenetic regulation of Neuregulin 1 promotes breast cancer progression associated to hyperglycemia

Nature Communications, Published online: 27 January 2023; doi:10.1038/s41467-023-36179-8Despite hyperglycemia has been associated to breast cancer, the underlying mechanisms are not completely understood. Here, the authors show that epigenetic regulation of Nrg1 gene during hyperglycemia promotes breast cancer development.

20h