Nature Communications

Nature Communications is an online-only, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, physical and chemical sciences. Papers published by the journal represent important advances of significa

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Realization of acoustic spin transport in metasurface waveguides

Nature Communications, Published online: 18 September 2020; doi:10.1038/s41467-020-18599-ySpin angular momenta play a crucial role in topological phases of matter, in acoustic waves they have been demonstrated recently. Here, the authors present a symmetry-breaking metasurface waveguide that assists backscattering suppression of acoustic waves, because...

Ultrasensitive and visual detection of SARS-CoV-2 using all-in-one dual CRISPR-Cas12a assay

Nature Communications, Published online: 18 September 2020; doi:10.1038/s41467-020-18575-6Rapid and early detection of SARS-CoV-2 will aid intervention to stop disease spread. Here the authors present a one-pot CRISPR-based rapid detection system with visual readout.

Structural and mechanistic basis of capsule <i>O</i>-acetylation in <i>Neisseria meningitidis</i> serogroup A

Nature Communications, Published online: 18 September 2020; doi:10.1038/s41467-020-18464-yNeisseria meningitidis capsular polysaccharide (CPS) is a major virulence factor and vaccine formulations against Neisseria meningitidis serogroup A (NmA) contain O-acetylated CPS. Here, the authors provide mechanistic insights into CPS O-acetylation in NmA by...

SPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells

Nature Communications, Published online: 18 September 2020; doi:10.1038/s41467-020-18549-8Cancer stem cells can evade treatment. Here, the authors perform an in vitro screen to identify proteins that are involved in protecting glioma cancer stem cells from therapy and find that SPT6 increases BRCA1 expression and drives error-free DNA repair, thereby...

Retrieving functional pathways of biomolecules from single-particle snapshots

Nature Communications, Published online: 18 September 2020; doi:10.1038/s41467-020-18403-xThere is a great interest in retrieving functional pathways from cryo-EM single-particle data. Here, the authors present an approach that combines cryo-EM with advanced data-analytical methods and molecular dynamics simulations to reveal the functional pathways...

Three-dimensional strain dynamics govern the hysteresis in heterogeneous catalysis

Nature Communications, Published online: 18 September 2020; doi:10.1038/s41467-020-18622-2Direct visualisation of site-specific strain variations of catalysts is needed to better understand catalytic properties. Here, the authors determine with attojoule precision that the well-known catalytic hysteresis phenomenon occurs at single particle level and...

DsbA-L mediated renal tubulointerstitial fibrosis in UUO mice

Nature Communications, Published online: 18 September 2020; doi:10.1038/s41467-020-18304-zDsbA-L upregulation prevents lipid-induced renal injury in diabetic nephropathy. Here, the authors show that DsbA-L knockout attenuates tubulointerstitial fibrosis in mice, and show that this occurs via activation of Smad3 and p53, which result in modulation of...

An integrated personal and population-based Egyptian genome reference

Nature Communications, Published online: 18 September 2020; doi:10.1038/s41467-020-17964-1North Africans are underrepresented in current genome-wide data sets. Here, the authors provide an Egyptian genome reference, consisting of de novo assembly of the genome of an Egyptian individual and genome-wide genetic variation from a representative cohort of...

A quantitative framework reveals ecological drivers of grassland microbial community assembly in response to warming

Nature Communications, Published online: 18 September 2020; doi:10.1038/s41467-020-18560-zStudies of microbial community assembly mechanisms typically use metrics for turnover within the whole community. Here, the authors develop an alternative approach based on turnover within lineages and dissect mechanistic change in grassland bacterial assembly...

Electron hydrodynamics in anisotropic materials

Nature Communications, Published online: 18 September 2020; doi:10.1038/s41467-020-18553-yIn some materials electrons can behave hydrodynamically, exhibiting phenomena associated with classical viscous fluids. In this theory work, the authors show that the symmetries of the crystal lattices in which the electrons reside can lead to additional unique...

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