Nature Neuroscience, Published online: 18 April 2024; doi:10.1038/s41593-024-01632-4As Nature Neuroscience celebrates its 25th anniversary, we are having conversations with both established leaders in the field and those earlier in their careers to discuss how the field has evolved and where it is heading. This month we are talking to Fernando de Castro...

Nature Neuroscience, Published online: 18 April 2024; doi:10.1038/s41593-024-01620-8Neuroinflammation and microglia significantly contribute to Alzheimer’s disease pathology, depending on their activation state. We found that TREM2-expressing microglia are a heterogenous population spanning activated to senescent cells.

Nature Neuroscience, Published online: 17 April 2024; doi:10.1038/s41593-024-01637-zLarry J. Young (1967–2024)

Nature Neuroscience, Published online: 16 April 2024; doi:10.1038/s41593-024-01644-0Author Correction: Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment

Nature Neuroscience, Published online: 10 April 2024; doi:10.1038/s41593-024-01629-zThe study of the female brain during pregnancy and motherhood is gaining traction, and holds the potential to address the unmet needs of millions of women worldwide. Here we highlight the most pressing gaps in this field. Filling these knowledge gaps will require two...

Nature Neuroscience, Published online: 10 April 2024; doi:10.1038/s41593-024-01619-1Using human iPSC-derived and mouse neurons, this study demonstrates that mRNA transport on lysosome-related vesicles is critical for the maintenance of axonal homeostasis and that its failure causes axonal degeneration.