Cell Death Dis. 2024 May 1;15(5):306. doi: 10.1038/s41419-024-06690-x.ABSTRACTColorectal cancers (CRCs) are highly heterogeneous and show a hierarchical organization, with cancer stem cells (CSCs) responsible for tumor development, maintenance, and drug resistance. Our previous studies showed the importance of thyroid hormone-dependent signaling on...

Clin Imaging. 2024 Apr 20;110:110162. doi: 10.1016/j.clinimag.2024.110162. Online ahead of print.ABSTRACTPURPOSE: Because incidental thyroid nodules (ITNs) are common extrapulmonary findings in low-dose computed tomography (LDCT) scans for lung cancer screening, we aimed to investigate the frequency of ITNs on LDCT scans separately on baseline and annual...

Adv Mater. 2024 May 1:e2313991. doi: 10.1002/adma.202313991. Online ahead of print.ABSTRACTDNA double-strand breaks (DSBs) yield highly determines radiotherapy efficacy. However, improving the inherent radiosensitivity of tumour DNA to promote radiation-induced DSBs remains a challenge. Using theoretical and experimental models, we discover the underexplored...

Updates Surg. 2024 May 1. doi: 10.1007/s13304-024-01851-1. Online ahead of print.ABSTRACTDifferentiated thyroid cancer (DTC) is the most common endocrine malignancy, with a rising incidence worldwide. Accurate prognostic models are essential for effective patient management. This study evaluates the prognostic value of various lymph node staging systems...

Am J Hum Genet. 2024 Apr 26:S0002-9297(24)00121-6. doi: 10.1016/j.ajhg.2024.04.006. Online ahead of print.ABSTRACTPapillary thyroid cancer (PTC) is the most common endocrine malignancy. 10% to 15% of individuals show familial clustering with three or more affected members, but the factors underlying this risk are unknown. In a group of recently studied...

Int J Surg Case Rep. 2024 Apr 20;119:109670. doi: 10.1016/j.ijscr.2024.109670. Online ahead of print.ABSTRACTINTRODUCTION AND IMPORTANCE: There are only a few case reports to date that have described patients with three or more multiple primary tumors. However, they have been reported more in the last decade, so a precise screening in patients with...