J Clin Endocrinol Metab. 2022 Apr 16:dgac233. doi: 10.1210/clinem/dgac233. Online ahead of print.ABSTRACTPURPOSE: People characterized as late chronotype have elevated type 2 diabetes and cardiovascular disease risk compared to early chronotype. It is unclear how chronotype is associated with insulin sensitivity, metabolic flexibility, or plasma TCA...

J Clin Endocrinol Metab. 2022 Apr 16:dgac235. doi: 10.1210/clinem/dgac235. Online ahead of print.ABSTRACTOBJECTIVE: To investigate the associations of different types of lower-carbohydrate diets with mortality among individuals with type 2 diabetes (T2D).METHODS: The prospective study included 5,677 patients with T2D. The overall, unhealthy, and healthy...

J Clin Endocrinol Metab. 2022 Apr 16:dgac232. doi: 10.1210/clinem/dgac232. Online ahead of print.ABSTRACTCONTEXT: Premenopausal women with idiopathic osteoporosis (PreMenIOP) have marked deficits in bone density, microstructure and strength.OBJECTIVE: To define effects of treatment with teriparatide followed by denosumab on Lumbar Spine (LS) volumetric...

J Clin Endocrinol Metab. 2022 Apr 16:dgac231. doi: 10.1210/clinem/dgac231. Online ahead of print.ABSTRACTCONTEXT: It is still debated whether prolonged use of proton pump inhibitors (PPIs) might affect metabolic health.OBJECTIVE: To investigate the relationship between prolonged use of PPIs and the risk of developing diabetes.METHODS: We performed a...

J Clin Endocrinol Metab. 2022 Apr 16:dgac217. doi: 10.1210/clinem/dgac217. Online ahead of print.ABSTRACTPURPOSE: The objectives of the ongoing, Phase 3, open-label extension trial enliGHten are to assess the long-term safety and efficacy of weekly administered long-acting growth hormone (LAGH) lonapegsomatropin in children with growth hormone deficiency...

J Clin Endocrinol Metab. 2022 Apr 15:dgac211. doi: 10.1210/clinem/dgac211. Online ahead of print.NO ABSTRACTPMID:35427422 | DOI:10.1210/clinem/dgac211