by Paula Ana Iribarren, Lucía Ayelén Di Marzio, María Agustina Berazategui, Andreu Saura, Lorena Coria, Juliana Cassataro, Federico Rojas, Miguel Navarro, Vanina Eder Alvarez Trypanosoma brucei are protozoan parasites that cause sleeping sickness in humans and nagana in cattle. Inside the mammalian host, a quorum sensing-like mechanism coordinates...

by Madison A. Youngblom, Tracy M. Smith, Holly J. Murray, Caitlin S. Pepperell Mycobacterium tuberculosis (M. tb), the causative agent of tuberculosis (TB), is a leading global cause of death from infectious disease. Biofilms are increasingly recognized as a relevant growth form during M. tb infection and may impede treatment by enabling bacterial...

by Tin Phan, Carolin Zitzmann, Kara W. Chew, Davey M. Smith, Eric S. Daar, David A. Wohl, Joseph J. Eron, Judith S. Currier, Michael D. Hughes, Manish C. Choudhary, Rinki Deo, Jonathan Z. Li, Ruy M. Ribeiro, Ruian Ke, Alan S. Perelson, for the ACTIV-2/A5401 Study Team To mitigate the loss of lives during the COVID-19 pandemic, emergency use authorization...

by Zimu Qiao, Jin Wang, Kaiyun Huang, Honghao Hu, Zhouhang Gu, Qiansheng Liao, Zhiyou Du As a type of parasitic agent, satellite RNAs (satRNAs) rely on cognate helper viruses to achieve their replication and transmission. During the infection of satRNAs, helper virus RNAs serve as templates for synthesizing viral proteins, including the replication...

by Yaru Zhou, Xuezhang Tian, Shaowei Wang, Ming Gao, Chuchu Zhang, Jiali Ma, Xi Cheng, Lei Bai, Hai-Bin Qin, Min-Hua Luo, Qingsong Qin, Baishan Jiang, Ke Lan, Junjie Zhang Kaposi’s sarcoma-associated herpesvirus (KSHV) is a double-stranded DNA virus etiologically associated with multiple malignancies. Both latency and sporadic lytic reactivation...

by David VanInsberghe, Dillon S. McBride, Juliana DaSilva, Thomas J. Stark, Max S. Y. Lau, Samuel S. Shepard, John R. Barnes, Andrew S. Bowman, Anice C. Lowen, Katia Koelle Patterns of within-host influenza A virus (IAV) diversity and evolution have been described in natural human infections, but these patterns remain poorly characterized in non-human...