Dr. Hans-Reimer RodewaldCredit: DKFZGerman researchers develop a way to equip mouse hematopoietic (blood) stem cells with a fluorescent marker that can be switched on from the outside. Using this tool, they were able to observe, for the first time, how stem cells mature into blood cells under normal conditions in a living organism.In the bone marrow,...

Demyelination by multiple sclerosis. The CD68 colored tissue shows several macrophages in the area of the lesion. Original scale 1:100New study reveals that hematopoietic stem cell transplants may be more effective than the drug mitoxantrone for people with severe cases of multiple sclerosis.The study appears in the online issue of Neurology®, the medical...

Global Stem Cells Group announced yesterday that it has signed a memorandum of understanding with the Regenerative Technology Alliance (RTA) to evaluate and promote stem cell training programs.Global Stem Cells Group and the Regenerative Technology Alliance (RTA) have signed a memorandum of understanding to evaluate and promote stem cell training programs.RTA,...

Inside the cell, calcium ions are released from a structure called the endoplasmic reticulum (ER). Forces applied to the bead cause ion channels in the ER to open mechanically (shown in red above), rather through biochemical signaling chemically (shown in green below). Credit: Jie Sun/Peter Wang research groupBy using optical tweezers to squeeze a tiny...

Hans-Peter KiemCreditBlood vessel cells improve the conversion of pluripotent stem cells like iPSCs to blood lineages.Hematopoietic stem cells (HSCs) can differentiate into all the kinds of ce ls that comprise the blood and immune cell lineages. For decades now, hematopoietic stem cell transplantation is the only viable option for certain blood disorders,...

Location and appearance of two example intestinal tumorsResearchers identify signaling molecules in intestinal stem cells that can give rise to cancer stem cells and tumors if left unregulated. The research suggests a new approach to targeting intestinal cancers.Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) announced today...