Economic sanctions, a tool long used to influence national policies for global peace and security, now demand urgent attention due to their severe, unintended consequences on population health. Studies reveal that economic sanctions reduce life expectancy by 1·4 years,1 deepen inequalities, and worsen health and economic conditions. However, potential...

We commend the Lancet Commission on Investing in Health for providing a substantive analysis of progress and future prospects for global health.1 Beginning in 1993 with the World Bank's influential report on investing in health, a series of timely analyses2–4 have documented substantial improvements in life expectancy and wellbeing over past decades,...

Short-course induction chemotherapy followed by chemoradiotherapy significantly improves survival of patients with locally advanced cervical cancer.

In Global Health 2050, the Lancet Commission on Investing in Health concludes that dramatic improvements in human welfare are achievable by mid-century with focused health investments. By 2050, countries that choose to do so could reduce by 50% the probability of premature death in their populations—ie, the probability of dying before age 70 years—from...

Locally advanced cervical cancer remains a substantial source of mortality, particularly in low-resource settings.1 Once-a-week cisplatin with external beam radiation followed by intracavitary or interstitial brachytherapy was established in 1999 as the standard of care2 and has not been altered by four large, international trials3–6 or by previous...

There are huge studies of human genetics and health, but almost all are focused on people of European origin. The Genes & Health Study aims to be different. Talha Burki reports.