This research develops bio-inspired hemostatic materials, achieving pseudo-active blood coagulation through the CHI-C/Geln sponge. Utilizing chitosan and gelatin, this two-layer configuration maximizes hemostatic capability without conventional coagulation proteins. The CHI-C/Geln sponge demonstrates excellent blood clotting efficacy and exceptional...

Abstract As an alternative to tissue adhesives, photochemical tissue bonding has been investigated for advanced wound healing. However, these techniques suffer from relatively slow wound healing with bleeding and bacterial infections. Here, we present the versatile attributes of afterglow luminescent particles (ALPs) embedded in dopamine-modified hyaluronate...

Abstract Due to the reduced absorption, light scattering, and tissue autofluorescence in the NIR-II (1000–1700 nm) region, significant efforts are underway to explore diverse material platforms for in vivo fluorescence imaging, particularly for cancer diagnostics and image-guided interventions. Of the reported imaging agents, nanoparticles derived...

Abstract Virion-mediated outbreaks are imminent and despite rapid responses, continue to cause adverse symptoms and death. Therefore, tunable, sensitive, high-throughput assays are needed to help diagnose future virion-mediated outbreaks. Herein, we developed a tunable in situ assay to selectively enrich virions and extracellular vesicles (EVs) and...

Polymeric electrode materials present exciting new opportunities in the design and fabrication of next-generation electrode arrays. This review examines the recent developments in polymeric electrode materials and the variety of approaches they enable for fabrication of bionic devices. Their application as stimulating and recording electrodes is presented....

A nano-drug delivery system is developed with the properties of active targeting to atherosclerotic plaques and pH-controlled drug release. It simultaneously inhibits the activation of NF-κB pathway in B cells and NLRP3 inflammasome in macrophages, leading reduced inflammation and depleted B cells. This strategy of anti-inflammation by regulating...