To the Editor We read with interest the recent article that reported among comatose patients with suspected acute poisoning, a conservative strategy of withholding intubation was associated with a greater clinical benefit for the composite end point of in-hospital death, length of ICU stay, and length of hospital stay. We think that some methodological...

This Viewpoint discusses the challenges involved with secondary health care data collection vs primary data collection and provides a list of suggested data checks before registration of a study protocol using secondary data.

People who received a SARS-CoV-2 vaccination had a lower risk of heart failure and blood clots in their veins and arteries after COVID-19 infection than those who had not been vaccinated, a recent study involving more than 20 million participants in Estonia, Spain, and the UK found.

Listen to the JAMA Editor’s Audio Summary for an overview and discussion of the important articles appearing in this week’s issue of JAMA.

Amid an uptick in measles cases and outbreaks both in the US and abroad, the US Centers for Disease Control and Prevention (CDC) issued an alert on March 18 encouraging clinicians to work with schools and educators to ensure children are up-to-date on their measles-mumps-rubella (MMR) vaccines. As of March 28, 97 measles cases had been reported in 18...