Wiley Online Library : Epilepsia
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“Is it a seizure?” Prediction tool for seizure likelihood in children aged 1–24 months admitted for electroencephalographic monitoring of paroxysmal, rhythmic, and repetitive events

Abstract Objective Paroxysmal, rhythmic, and repetitive events (PRREs) during infancy can be concerning for possible seizures, especially following perinatal brain injuries. The workup for establishing whether a PRRE represents a seizure involves the use of continuous video-electroencephalography (cVEEG) for event characterization. This study aims...

Thu May 30, 2024 10:46
Cannabidiol‐enriched oil for adult patients with drug‐resistant epilepsy: Prospective clinical and electrophysiological study

Abstract Objective Cannabidiol-enriched oil (CBDO) is being used increasingly to improve seizure control in adult patients with drug-resistant epilepsy (DRE), despite the lack of large-scale studies supporting its efficacy in this patient population. We aimed to assess the effects of add-on CBDO on seizure frequency as well as on gait, cognitive,...

Thu May 30, 2024 10:46
Socioeconomic differences in use of antiseizure medication in pregnancies with maternal epilepsy: A population‐based study from Nordic universal health care systems

Abstract Objective Research points to disparities in disease burden and access to medical care in epilepsy. We studied the association between socioeconomic status (SES) and antiseizure medication (ASM) use in pregnancies with maternal epilepsy. Methods We conducted a cross-sectional study consisting of 21 130 pregnancies with maternal epilepsy...

Wed May 29, 2024 10:57
ArcKR expression modifies synaptic plasticity following epileptic activity: Differential effects with in vitro and in vivo seizure‐induction protocols

Abstract Objectives Pathological forms of neural activity, such as epileptic seizures, modify the expression pattern of multiple proteins, leading to persistent changes in brain function. One such protein is activity-regulated cytoskeleton-associated protein (Arc), which is critically involved in protein-synthesis–dependent synaptic plasticity underlying...

Wed May 29, 2024 10:57
Global modified‐Delphi consensus on comorbidities and prognosis of SCN8A‐related epilepsy and/or neurodevelopmental disorders

Abstract Objectives We aimed to develop consensus on comorbidities (frequency, severity, and prognosis) and overall outcomes in epilepsy, development, and cognition for the five phenotypes of SCN8A-related disorders. Methods A core panel consisting of 13 clinicians, 1 researcher, and 6 caregivers was formed and split into three workgroups. One group...

Tue May 28, 2024 12:09

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