Abstract Recently, the pathomechanisms of keloids have been extensively researched using transcriptomic analysis, but most studies did not consider the activity of keloids. We aimed to profile the transcriptomics of keloids according to their clinical activity and location within the keloid lesion, compared with normal and mature scars. Tissue samples...

Abstract Hidradenitis Suppurativa (HS) is a chronic autoinflammatory skin disease with activated keratinocytes, tunnel formation and a complex immune infiltrate in tissue. The HS microbiome is polymicrobial with an abundance of commensal gram-positive facultative (GPs) Staphylococcus species and gram-negative anaerobic (GNA) bacteria like Prevotella,...

Experimental Dermatology, Volume 33, Issue 5, May 2024.

Experimental Dermatology, Volume 33, Issue 5, May 2024.

In this study, a large number of images of psoriasis were collected in multiple clinical centrers, and our research selects the optimal algorithms to achieve the best balance of accuracy and speed, ensuring the feasibility of the model. Finally, we proposed an intelligent PASI app that can assist dermatologists in long-term and objective PASI scoring....

Abstract Cutaneous squamous cell carcinoma (cSCC) is the second most common malignancy worldwide, with most deaths caused by locally advanced and metastatic disease. Treatment of resectable metastases is typically limited to invasive surgery with adjuvant radiotherapy; however, many patients fail to respond and there is minimal data to predict response...