To the Editor We read the article by Brüggen et al that outlined international consensus guidelines for the management of drug rash with eosinophilia and systemic symptoms (DRESS) with great interest. These were the first guidelines published that formally recommended routine screening for human herpesviruses: cytomegalovirus (CMV), Epstein-Barr virus,...

This consensus statement develops an international definition and diagnostic criteria for generalized pustular psoriasis using the modified Delphi model.

This cohort study examines the association between methotrexate use and interstitial lung disease in patients with dermatomyositis.

In Reply We appreciate the interest in and valuable thoughts of Zhu et al on our international Delphi consensus on the treatment of adult patients with drug reaction with eosinophilia and systemic symptoms (DRESS). We thank them for their reflections on the role of human herpesvirus 6 (HHV-6) reactivation in DRESS. The authors address 3 important points.

A man with a history of polysubstance use presents with new bullae on his bilateral lower extremities. What is your diagnosis?

To the Editor It is with great interest that we read the recent article by Xu et al that described 2 infants with systemic histiocytic neoplasms harboring ALK translocations who were successfully treated with the ALK inhibitor alectinib. To our surprise, the authors classified the disease as systemic juvenile xanthogranuloma (JXG) without any mention...