Nature Biotechnology journal featuring biotechnology articles and science research papers of commercial interest in pharmaceutical, medical, and environmental sciences.
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Nature Biotechnology, Published online: 12 August 2022; doi:10.1038/s41587-022-01423-xThe application of CRISPR–Cas13 for targeted RNA degradation is hindered by the existence of collateral effects induced by Cas13. We screened hundreds of engineered Cas13 variants using a convenient and sensitive reporter system and obtained several variants with markedly...
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Nature Biotechnology, Published online: 12 August 2022; doi:10.1038/d41587-022-00007-zAfter >20 years of research at the intersection of virology and immunology, two brothers have launched a venture seeking to turn arenaviruses into an anticancer virotherapy.
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Nature Biotechnology, Published online: 11 August 2022; doi:10.1038/s41587-022-01419-7Several engineered Cas13 variants achieve targeted RNA degradation with minimal collateral effects.
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Nature Biotechnology, Published online: 11 August 2022; doi:10.1038/s41587-022-01408-wA bioengineered cornea made of collagen restores vision in a pilot clinical study.
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Nature Biotechnology, Published online: 11 August 2022; doi:10.1038/s41587-022-01409-9Porcine dermal collagen was chemically and photochemically bioengineered into an implantable tissue mimicking the human corneal extracellular matrix. The implant presents a simpler and safer method than donor cornea transplantation while delivering equivalent outcomes,...
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