Wiley Online Library : Small
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Nanoparticles Coated with Brain Microvascular Endothelial Cell Membranes can Target and Cross the Blood–Brain Barrier to Deliver Drugs to Brain Tumors

The blood-brain barrier (BBB) is composed of tightly interconnected brain microvascular endothelial cells (BMECs), which hinder effective drug delivery to the glioblastoma (GBM). By coating with bEnd3-line BMEC membrane, the DOX-loaded BM-PDs exhibit specific targeting properties toward BMECs and demonstrate efficient transcytosis across the BBB....

Sat Feb 24, 2024 12:01
TiN as Radical Scavenger in Fe─N─C Aerogel Oxygen Reduction Catalyst for Durable Fuel Cell

This work presents a TiN-doped Fe─N─C aerogel via the sol–gel method for the oxygen reduction reaction (ORR) in PEMFC. The TiN can eliminate the radical intermediates while Fe single-atoms catalyze the ORR. The rational design that combines the advantages of Fe single-atom, TiN radical scavenger, and highly porous network enables a durable and active...

Sat Feb 24, 2024 12:01
Non‐Covalent Interaction Enhancement on Active/Interfacial Layers via Two‐Dimensional Vermiculite Doping for Efficient Organic Solar Cells

The non-covalent interaction between the cathode interface layer and nonfullerene acceptor is enhanced by introducing vermiculite in the PFN-Br interlayer. As a result, the power conversion efficiency of organic solar cells based on PBDB-T:ITIC is boosted from 10.87% to 12.89%. Abstract Interface modification plays an important role in improving...

Sat Feb 24, 2024 12:01
Transepithelial Electrical Impedance Increase Following Porous Substrate Electroporation Enables Label‐Free Delivery

An integrated impedance measurement and porous substrate electroporation (PSEP) device is described. Impedance measurements from the device show transepithelial electrical impedance (TEEI) increases following PSEP, unlike other electroporation methods. A correlation between TEEI response and delivery outcomes is demonstrated, allowing assessment without...

Sat Feb 24, 2024 12:01
pH/H2O2 Cascade‐Responsive Nanoparticles of Lipid‐Like Prodrugs through Dynamic‐Covalent and Coordination Interactions for Chemotherapy

5-Fluorouracil-based lipid-like prodrug (5Fu-lipids) are constructed by B-N coordination and dynamic covalent borate ester bond. 5Fu-lipid nanoparticles (5Fu-LNPs) assembled by 5Fu-lipids exhibit pH/H2O2 cascade responsive properties in tumor microenvironment and good stability in neutral conditions. Besides, in vitro and in vivo experiments show...

Sat Feb 24, 2024 12:01
Interface‐Engineered NiFe/Ni‐S Nanoparticles for Reliable Alkaline Oxygen Production at Industrial Current: A Sulfur Source Confinement Strategy

A sulfur source confinement strategy is developed to integrate Ni3S2 onto the surface of amorphous/crystalline NiFe alloy nanoparticles (NiFe/Ni-S). The constructed NiFe/Ni-S delivers an ultra-low overpotential of 239 mV and the anion exchange membrane water electrolyzer incorporating NiFe/Ni-S demonstrates a 400 h stability at an industrial current...

Sat Feb 24, 2024 12:01

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