Deacylative Carbon‐Carbon Bond Cleavage of Ketone Equivalents: Applications to Radical Carbon‐Carbon Bond Formation Reactions

The synthetic application of ketone‐derived oxaziridines as alkyl radical precursors in copper‐catalyzed Carbon‐Carbon bond formation reactions is described. Experimental and computational studies indicate a free radical mechanism, where alkyl radicals are efficiently generated via cleavage of a Carbon‐Carbon bond of oxaziridines. Acyclic and unstrained...

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Assembly of Water‐soluble AIE‐active Fluorescent Organic Nanoparticles for Ratiometric Detection of Hypochlorite in Living Cells

Water‐soluble AIE‐active fluorescent organic nanoparticles THG‐1 were synthesized and utilized for detection of exogenous and endogenous HOCl in living cells. Abstract Hypochlorous acid (HOCl) plays a crucial role in many physiological processes and is widely used as bleach, deodorant and fungicide. In this work, we designed an amphiphilic hydrazone...

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Switch‐On Diketopyrrolopyrrole‐Based Chemosensors for Cations Possessing Lewis Acid Character

For the first time diketopyrrolopyrroles (DPPs) have been synthesized directly from nitriles possessing (aza)crown ethers leading to macrocycle‐dye hybrids. Depending on the nature of the linkage between DPP and macrocyclic ring, various coordination effects are found. The strong interaction of the cations possessing Lewis acid character such as Li...

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One‐dimensional crystalline channels with well‐defined active metal centers hold great potential as heterogeneous catalysts. Herein, the results of a mechanistic study of photoinduced olefin migration reactions at palladium sites arranged on the channel ceiling of a porous metal‐macrocycle framework are described. Experimental and theoretical studies...

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Study and Comparison on Purification Methods of Multicolor Emission Carbon Dots

Recent years have witnessed a rapid development of carbon dots (CDs), due to their outstanding luminescence properties and excellent biocompatibility. However, the internal structure and photoluminescent (PL) mechanism of CDs are still the subject of considerable debate, which is due to the fact that reaction products usually contain mixtures of several...

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Improved Synthesis of ortho‐Phenylene‐bridged Cyclic Tetrapyrroles and Oxidative Fusion Reactions Toward Substituted Tetraaza[8]circulenes

Hetero[8]circulenes have emerged as novel functionalized heteronanographenes that show various promising functions such as bright fluorescence, charge transporting, and redox reactivities. One of the effective synthetic strategy is the fold‐in type oxidative fusion reaction of ortho‐phenylene‐bridged cyclic tetrapyrroles, whose construction, however,...

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Post‐synthetic ‘click’ synthesis of RAFT polymers with pendant self‐immolative triazoles

Self‐immolative linkers offer efficient mechanisms for deprotecting ‘caged’ functional groups in response to specific stimuli. Herein we describe a convenient ‘click’ chemistry method for introducing pendant self‐immolative linkers to a polymer backbone through post‐polymerization modification. The introduced triazole rings serve both to anchor the...

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Natural Cellulose Substance Based Energy Materials

The natural cellulose substances have been proven to be ideal structural templates and scaffolds for the fabrication of artificial functional materials with designed structures, psychochemical properties and functionalities. The natural cellulose substances own unique hierarchically porous network structures with flexible, biocompatible, and environmental...

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The Emergence of Palladium‐Catalyzed C(sp3)‐H Functionalization of Free Carboxylic Acids

Palladium‐catalyzed directing group assisted C–H bond activation has emerged as a powerful tool in synthetic organic chemistry. However, only recently, among various directing groups, widely available carboxylate moiety is recognized as a versatile candidate for the regioselective transformations. Notably, palladium‐catalyzed carboxylate directed C‐(sp3...

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Revealing minor pH changes of mitochondria by a highly sensitive molecular fluorescent probe

Mitochondrial pH is an important factor associated with cellular metabolism and pathological states. Thus, sensitively monitoring its minor change was essential. However, it was challengeable due to the lack of suitable probes. Here, a mitochondria‐targeted probe ( NIR‐OH‐1 ) was synthesized. Based on the protonation/deprotonation of the hydroxy group...

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