Our study identified a subset of B-ALL patients with multilineage involvement. It is imperative to be aware of this phenomenon for accurate disease burden assessment during monitoring to avoid unnecessary treatment. Aims B lymphoblastic leukaemia/lymphoma (B-ALL) is thought to originate from Pro/Pre-B cells and the genetic aberrations largely...

The intratumour stroma proportion (iTPS) may predict the response of NSCLC patients to first-line ICIs in combination with chemotherapy. The figure shows stroma-L (A) and stroma-H (B) of lung squamous cell carcinoma; stroma-L (C) and stroma-H (D) of lung adenocarcinoma (the outlined area is the tumour area, while the remaining part is the tumour stroma)....

For small invasive carcinomas arising from intraductal papillary mucinous neoplasms (IPMNs), the microscopic size of the largest invasive focus (LS) optimally stratifies recurrence-free and overall survival at a threshold of 1.5 cm. Aims Small invasive carcinomas arising in intraductal papillary mucinous neoplasms (IPMNs) of the pancreas can...

In our cohort of 423 fine-needle core biopsies of the pancreas, the median diagnostic tissue amount was 30%. Common histological findings included desmoplasia (36%), single atypical cells (44%), haphazard glandular growth pattern (68%), nuclear pleomorphism > 4:1 (39%) and incomplete gland lumens (18%). A total of 343 (81%) were linked to a final...

Histopathology, Volume 84, Issue 7, Page 1092-1094, June 2024.

Histopathology, Volume 84, Issue 7, Page 1077-1078, June 2024.