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Lubricant Shots for Knee OA: No, They Really Don't Help

(MedPage Today) -- Researchers analyzing previous trials of hyaluronic acid injections for knee osteoarthritis (OA) found that, although measurable benefit was demonstrated, it was too small to be clinically relevant. Pooled data from 24 large...

CEND-1 Offers Hope in Advanced Pancreatic Cancer

(MedPage Today) -- Chemotherapy combined with the CEND-1 cyclic peptide showed promising efficacy, and was well tolerated as a first-line treatment, for patients with metastatic pancreatic cancer, researchers reported. In a phase I study of 29...

Bust for Balovaptan in Treatment of Childhood Autism

(MedPage Today) -- An oral selective vasopressin 1a (V1a) receptor antagonist failed at improving socialization and communication among those with pediatric autism spectrum disorder (ASD) in a randomized, double-blind study. When compared with...

FDA Getting Tougher on Birth Tissue Companies

(MedPage Today) -- The FDA may be getting tougher on birth tissue injection companies, experts in stem cells and regenerative medicine said. In its most recent warning letter to one such company, Re-Gen Active Lab, FDA stated outright that use...

Memoirs of a 'Recovering' Peer Reviewer

(MedPage Today) -- In theory, the application of evidenced-based guidelines assists in reducing unwarranted variation in clinical practice and improving the quality and cost of care. Guideline developers, health plans, and their benefit managers...

Fewer Complications With Robotic Nephrectomy in Complex Kidney Tumors

(MedPage Today) -- Robotic-assisted partial nephrectomy (RAPN) led to a lower rate of complications compared with open partial nephrectomy (OPN) in patients with intermediate- or high-complexity kidney tumors, the randomized OpeRa trial found...

Hypothyroidism May Predict Dementia in Golden Years

(MedPage Today) -- Older people with a history of hypothyroidism may be at a much higher risk for developing dementia, a Taiwanese study found. Among patients ages 65 and older, hypothyroidism was linked with an 81% increased risk of being diagnosed...

Anti-LAG-3, Pembrolizumab Doublet Continues to Impress in Metastatic NSCLC

(MedPage Today) -- At the recent American Society of Clinical Oncology (ASCO) annual meeting, updated results of a phase II trial showed that the lymphocyte activation gene (LAG)-3 inhibitor eftilagimod alpha in combination with pembrolizumab ...

People With Gum Disease Are More Prone to Heart Failure

(MedPage Today) -- The link between periodontal disease and heart failure (HF) was reinforced by long-term data from the Atherosclerosis Risk in Communities (ARIC) cohort. Among study participants with full-mouth periodontal exams in 1996-1998...

ASCO 2032: What Will Be the Big Story in Lung Cancer?

(MedPage Today) -- New clinical research unveiled at the recent American Society of Clinical Oncology (ASCO) annual meeting has the potential to significantly alter the treatment of lung cancer. But what will be the innovations we are talking about...

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