Nature Methods is a science methodology journal publishing laboratory techniques and methods papers in the life sciences and areas of chemistry relevant to the life sciences.
Nature Methods, Published online: 18 October 2021; doi:10.1038/s41592-021-01270-9This Perspective discusses how neuroscience can benefit from harnessing nanoscience-based tools for manipulating and recording neuronal activity.
Nature Methods, Published online: 15 October 2021; doi:10.1038/s41592-021-01290-5MethodsJ2: a software tool to capture metadata and generate comprehensive microscopy methods text
Nature Methods, Published online: 15 October 2021; doi:10.1038/s41592-021-01302-4The exception proves the rule.
Nature Methods, Published online: 14 October 2021; doi:10.1038/s41592-021-01285-2DeepInterpolation is a self-supervised deep learning-based denoising approach for calcium imaging, electrophysiology and fMRI data. The approach increases the signal-to-noise ratio and allows extraction of more information from the processed data than from the raw data.
Nature Methods, Published online: 11 October 2021; doi:10.1038/s41592-021-01288-zMDEmic: a metadata annotation tool to facilitate management of FAIR image data in the bioimaging community
Nature Methods, Published online: 04 October 2021; doi:10.1038/s41592-021-01294-1Researchers develop single-cell SPRITE to detect higher-order 3D genome structures in single cells.
Nature Methods, Published online: 04 October 2021; doi:10.1038/s41592-021-01300-6Community-driven initiatives are proposing standards to improve the reporting and reproducibility of machine learning in biology. We support these developments, some of which are described in this month’s special issue.
Nature Methods, Published online: 04 October 2021; doi:10.1038/s41592-021-01297-yNanoporeTERs, engineered reporter proteins, can be detected on MinION nanopore sensor arrays.
Nature Methods, Published online: 04 October 2021; doi:10.1038/s41592-021-01296-zReprogrammed natural killer cells show enhanced functional properties and anti-tumor efficacy.
Nature Methods, Published online: 04 October 2021; doi:10.1038/s41592-021-01295-0A deep-learning-based tool and a large ground truth dataset enable spike inference from calcium imaging data acquired in a variety of experimental conditions.
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