T cell antigen discovery

Nature Methods, Published online: 06 July 2020; doi:10.1038/s41592-020-0867-zA review on recent method development for discovering T cell antigens.

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ZipSeq: barcoding for real-time mapping of single cell transcriptomes

Nature Methods, Published online: 06 July 2020; doi:10.1038/s41592-020-0880-2ZipSeq uses patterned illumination and photocaged oligonucleotides to serially print barcodes onto live, intact tissues for spatially mapping single cell transcriptomes.

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Selective cell-surface N-glycan editing

Nature Methods, Published online: 02 July 2020; doi:10.1038/s41592-020-0896-7A two-step chemoenzymatic method for N-glycan subtype-selective editing.

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GemSpot allows modeling of ligands in cryo-EM maps

Nature Methods, Published online: 02 July 2020; doi:10.1038/s41592-020-0900-2GemSpot allows modeling of ligands in cryo-EM maps

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Why Black lives matter in science

Nature Methods, Published online: 02 July 2020; doi:10.1038/s41592-020-0908-7Systemic racism has held back under-represented minorities, especially Black people, in scientific research. We’re committed in our roles as journal editors to help correct this inequality.

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A new way to see RNAs

Nature Methods, Published online: 02 July 2020; doi:10.1038/s41592-020-0888-7Producing reliable atomic- or close-to-atomic-resolution structures of RNA-only molecules has been a formidable task. Ribosolve can solve sub-nanometer-resolution cryo-EM structures of unbound RNA molecules with unprecedented accuracy and speed.

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Contamination in sequence databases

Nature Methods, Published online: 02 July 2020; doi:10.1038/s41592-020-0895-8A fast algorithm detects unexpected contamination events in public databases.

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Sugar-coating dendritic cells

Nature Methods, Published online: 02 July 2020; doi:10.1038/s41592-020-0892-yIn situ labeling with azido sugars enables in vivo immunomodulation of dendritic cells.

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Expanding worms

Nature Methods, Published online: 02 July 2020; doi:10.1038/s41592-020-0898-5Expanding worms

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A clearer view of mitophagy

Nature Methods, Published online: 02 July 2020; doi:10.1038/s41592-020-0903-zA clearer view of mitophagy

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