Cell-mimicking nanodecoys neutralize SARS-CoV-2 and mitigate lung injury in a non-human primate model of COVID-19

Nature Nanotechnology, Published online: 17 June 2021; doi:10.1038/s41565-021-00923-2In this paper the authors show that nanovesicles coated with lung spheroid cell membranes expressing angiotensin-converting enzyme 2 can bind the spike protein of SARS-CoV-2, neutralizing the virus and preventing lung cell infections in murine and non-human primate...

1d

Conformation-sensitive targeting of lipid nanoparticles for RNA therapeutics

Nature Nanotechnology, Published online: 17 June 2021; doi:10.1038/s41565-021-00928-xWhile targeted lipid nanoparticles might allow partial delivery of genetic materials to non-hepatic cells, the selectivity of this approach is still unsatisfying. Here the authors functionalize their lipid nanoparticles with a targeting moiety that recognizes a protein...

1d

Flexo-photovoltaic effect in MoS₂

Nature Nanotechnology, Published online: 17 June 2021; doi:10.1038/s41565-021-00919-yA strain-gradient approach induced by the phase-change transition enables the observation of the flexo-photovoltaic effect in MoS2.

1d

Viscoelastic surface electrode arrays to interface with viscoelastic tissues

Nature Nanotechnology, Published online: 17 June 2021; doi:10.1038/s41565-021-00926-zBioelectronic interfacing with living tissues should match the biomechanical properties of biological materials to reduce damage to the tissues. Here, the authors present a fully viscoelastic microelectrode array composed of an alginate matrix and carbon-based nanomaterials...

1d

Continuous-wave near-infrared stimulated-emission depletion microscopy using downshifting lanthanide nanoparticles

Nature Nanotechnology, Published online: 14 June 2021; doi:10.1038/s41565-021-00927-yThe application of stimulated-emission depletion (STED) microscopy for deep-tissue imaging in the near-infrared optical window is challenged by high cellular autofluorescence. Here the authors present a lanthanide nanoprobe whose electronic configuration enables long-term...

4d

Environmental dimensions of the protein corona

Nature Nanotechnology, Published online: 11 June 2021; doi:10.1038/s41565-021-00924-1This Review presents the emerging understanding of the importance of the dynamic and evolving protein corona composition in mediating the fate, transport and biological identity of nanomaterials in the environment. Principles specific to the environment are presented,...

1w

Making nano data FAIR enough

Nature Nanotechnology, Published online: 11 June 2021; doi:10.1038/s41565-021-00935-yThe FAIR principles provide compelling guidelines on how to achieve reusability of nanotechnology data.

1w

X-ray-activated persistent luminescence nanomaterials for NIR-II imaging

Nature Nanotechnology, Published online: 10 June 2021; doi:10.1038/s41565-021-00922-3Persistent luminescence is a promising bioimaging technique that is not affected by background autofluorescence, but its in vivo application is challenged by the fact that the materials currently available are activated by high-energy light, with emission in the ultraviolet...

2w

Quantum tomography of an entangled three-qubit state in silicon

Nature Nanotechnology, Published online: 07 June 2021; doi:10.1038/s41565-021-00925-0Among the candidates for large-scale quantum computing devices, silicon-based spin qubits offer an outstanding nanofabrication capability for scaling-up. In an array of three spin qubits in silicon, high-fidelity state preparation and control enable the creation of...

2w

Ultra-fast non-volatile memory

Nature Nanotechnology, Published online: 07 June 2021; doi:10.1038/s41565-021-00932-1Van der Waals heterostructures serve as a platform for memory devices with ultra-fast writing speeds and non-volatile retention times, motivating their use in integrated circuits and systems.

2w