Brain Behav Immun Health. 2020 Nov 2;9:100169. doi: 10.1016/j.bbih.2020.100169. eCollection 2020 Dec.ABSTRACTTreatments for depression and mood disorders have been singularly targeted at the brain without consideration for the context of the rest of the body. As evidence mounts for a role of autoimmunity and inflammation as risk factors and contributors...

Nat Rev Gastroenterol Hepatol. 2021 Sep 27. doi: 10.1038/s41575-021-00512-7. Online ahead of print.ABSTRACTAutoimmune diseases, including inflammatory bowel disease, multiple sclerosis and rheumatoid arthritis, have distinct clinical presentations but share underlying patterns of gut microbiome perturbation and intestinal barrier dysfunction. Their...

Diseases. 2021 Sep 2;9(3):60. doi: 10.3390/diseases9030060.ABSTRACTIn recent years, probiotics have attracted public attention and transformed the social perception of microorganisms, convening a beneficial role/state on human health. With aging, the immune system, body physiology, and intestinal microbiota tend to change unfavorably, resulting in many...

Curr Med Chem. 2021 Sep 22. doi: 10.2174/0929867328666210922161913. Online ahead of print.ABSTRACTBACKGROUND: The role of gut microbiota in human disease is fascinating for hundreds of researchers worldwide. Many works have highlighted that gut microbiota modulates the immune system, and that its disruption can trigger autoimmune and inflammatory immune-mediated...

Pharmacol Ther. 2021 Sep 15:107988. doi: 10.1016/j.pharmthera.2021.107988. Online ahead of print.ABSTRACTThe human microbiota comprises trillions of symbiotic microorganisms and is involved in regulating gastrointestinal (GI), immune, nervous system and metabolic homeostasis. Recent observations suggest a bidirectional communication between the gut...

J Nutr Biochem. 2021 Sep 10:108863. doi: 10.1016/j.jnutbio.2021.108863. Online ahead of print.ABSTRACTAutoimmune hepatitis (AIH) is an immune-mediated type of chronic liver inflammation accompanied by intestinal flora imbalance. Probiotics have been reported to ameliorate imbalances in the intestinal flora. This study aimed to investigate the effects...