Abstract Background Type 2 diabetes mellitus (T2DM) may affect the oral microbial community, exacerbating periodontal inflammation; however, its pathogenic mechanisms remain unclear. As nucleotide-binding oligomerization domain 2 (NOD2) plays a crucial role in the activation during periodontitis (PD), it is hypothesized that changes in the oral microbial...

The cover image is based on the Original Article Primed inflammatory response by fibroblast subset is necessary for proper oral and cutaneous wound healing by Zhaoxu Chen et al., https://doi.org/10.1111/omi.12442.

Abstract Porphyromonas gingivalis produces five classes of serine/glycine lipids that are recovered in lipid extracts from periodontitis-afflicted teeth and diseased gingival tissues, particularly at sites of periodontitis. Because these lipids are recovered in diseased gingival tissues, the purpose of the present study was to evaluate the capacity...

Abstract Liver-X receptors (LXRs) are essential nuclear hormone receptors involved in cholesterol and lipid metabolism. They are also believed to regulate inflammation and physiological and pathological bone turnover. We have previously shown that infection with the periodontal pathogen Porphyromonas gingivalis (Pg) in mice increases the abundance...

Molecular Oral Microbiology, Volume 39, Issue 3, Page ii-iv, June 2024.

Molecular Oral Microbiology, Volume 39, Issue 3, Page 91-92, June 2024.