People with two copies of the gene variant APOE4 are almost certain to get Alzheimer’s, say researchers, who proposed a framework under which such patients could be diagnosed years before symptoms.

Donald J. Trump again broke a gag order meant to bar him from attacking participants in his criminal trial, Justice Juan M. Merchan ruled. He threatened the former president with jail.

The shipping company said the militia had recently tried to attack ships further from the shores of Yemen, putting more strain on logistics.

The former House speaker, responding to an Opinion essay, points to legislation pending in Congress.

Although a resident confessed to setting the August 2023 blaze that killed 76 people in a dilapidated building, a report found that officials had ignored warning signs for years.

Ursula Von der Leyen, the European Commission president, pushed Beijing to help rein in Russia’s war in Ukraine after meeting with the Chinese and French leaders in Paris.