ACT plus usual care is clinically effective for maintaining or improving quality of life in people with motor neuron disease. As further evidence emerges confirming these findings, health-care providers should consider how access to ACT, adapted for the specific needs of people with motor neuron disease, could be provided within motor neuron disease...

Motor neuron disease is a devastating incurable condition with a severe effect on autonomy and quality of life of patients and their relatives. Treatment primarily consists of marginally disease-modifying neuroprotective therapies, which include measures to alleviate disease-related symptoms such as muscle cramps, sialorrhoea, dysphagia and respiratory...

Ductal carcinoma in situ (DCIS) accounts for 15–25% of all breast cancer diagnoses. Its prognosis is excellent overall, the main risk being the occurrence of local breast events, as most cases of DCIS do not progress to invasive cancer. Systematic screening has greatly increased the incidence of this non-obligate precursor of invasion, lending urgency...

Partial or complete deficiency of anterior or posterior pituitary hormone production leads to central hypoadrenalism, central hypothyroidism, hypogonadotropic hypogonadism, growth hormone deficiency, or arginine vasopressin deficiency depending on the hormones affected. Hypopituitarism is rare and likely to be underdiagnosed, with an unknown but rising...

Highly pathogenic avian influenza A(H5N1) viruses (clade 2.3.4.4b) continue to evolve and spread in many countries.1 Since 2020, H5 influenza viruses have spread globally among wild birds,1 causing outbreaks in poultry,2 substantially impacting food safety and security.3,4 From birds, spillover events to terrestrial and marine mammals have occurred...

The term long COVID, also known as post-COVID-19 condition, was coined in spring, 2020, by individuals with ongoing symptoms following COVID-19 in response to unsatisfactory recognition of this emerging syndrome by health-care practitioners.1 In September to November, 2020, clinical codes for persistent post-COVID-19 condition and related referrals...